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Tuftsin

Known as: Tuftsin [Chemical/Ingredient], L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine, L-Thr-L-Lys-L-Pro-L-Arg 
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the spleen by enzymatic cleavage of a leukophilic gamma-globulin… 
National Institutes of Health

Related topics

Related topics

22 relations
ANDROGRAPHIS PANICULATA WHOLE 500 mg ORAL CAPSULE [AMPITREXYL]In BloodProcess of secretionagonists

Broader (1)

Immunologic Factors

Narrower (11)

N-cholestanyl-amino-ethyl-rigin amideN-palmitoyl-amino-ethyl-rigin amideTuftsin Deficiencyleukokininogen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Partial sequences of histones with tuftsin activity.
Tuftsin and six tuftsin analogues with the partial sequences of histones were synthesized by the classical method. Most of these… 
Review
2002
Review
2002
Superior Chemotherapeutic Efficacy of Amphotericin B in Tuftsin-bearing Liposomes against Leishmania Donovani Infection in Hamsters
Chemotherapeutic efficacy of the amphotericin B (Amp B), which is the drug of choice for treatment of the leishmanial infections… 
1999
1999
A reassessment of splenic hypofunction in celiac disease.
1991
1991
Immunostimulation by a partially modified retro-inverso-tuftsin analogue containing Thr1 psi[NHCO](R,S)Lys2 modification.
The tuftsin retro-inverso analogue H-Thr psi[NHCO](R,S)Lys-Pro-Arg-OH was synthesized through a novel procedure for the high… 
1988
1988
Substance P augmentation of CSF-1-stimulated in vitro myelopoiesis. A two-signal progenitor restricted, tuftsin-like effect.
The inflammatory neuropeptide substance P acted as a costimulant for macrophage CSF-1-induced clonal proliferation of murine… 
1986
1986
Isolation and subunit composition of tuftsin receptor.
Tuftsin (Thr-Lys-Pro-Arg) receptor was purified to apparent homogeneity by affinity chromatography, using a pentapeptide analog… 
Review
1983
Review
1983
Immunopharmacological Properties of Tuftsin and of Some Analogues
Since the description by Najjar and Nishioka' that the basic tetrapeptide (Thr-Lys-Pro-Arg), originating from a leukophilic IgG… 
1978
1978
In vivo immunostimulation by tuftsin
SummaryTuftsin, a physiological basic tetrapeptide known for its capacity to stimulate the phagocytic activity of macrophages and… 
Highly Cited
1977
Highly Cited
1977
Radioimmunoassay of the phagocytosis‐stimulating peptide tuftsin in normal and splenectomized subjects
A radioimmunoassay was developed for the phagocytosis‐stimulating peptide tuftsin, H‐Thr‐Lys‐Pro‐Arg‐OH, and preliminary results… 
1973
1973
TUFTSIN DEFICIENCY SYNDROME A Report of Two New Cases
Two families with deficiency in the phagocytosis stimulating peptide, tuftsin, are reported. Both cases gave a history of… 
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