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Coeliac disease
TLDR
The Marsh classification of intestinal coeliac lesions, as modified by Oberhuber et al, is used by most pathologists to evaluate the intestinal lesions of patients with CD, both for diagnosis and to assess the regression of the lesions after a gluten free diet.
Methodology and Indications of H2‐Breath Testing in Gastrointestinal Diseases: the Rome Consensus Conference
TLDR
The final statements, graded according to the level of evidence and strength of recommendation, identify the indications for the use of H2-breath testing in the clinical practice and methods to be used for performing the tests.
Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease
TLDR
It is suggested that IL-15 plays a crucial role in the generation of epithelial damage in active CD and has the potential to provide new therapeutic tools to prevent tissue damage and lymphomagenesis in CD.
An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity
TLDR
This prospective survey shows that non-celiac gluten sensitivity has a strong correlation with female gender and adult age, and the prevalence of NCGS seems to be only slightly higher than that of celiac disease.
Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma.
TLDR
IL-6 could be considered a promising tumor marker for HCC, in particular, the diagnostic value of the test is significantly increased when combined with A(1)FP.
Risk of non-Hodgkin lymphoma in celiac disease.
TLDR
Celiac disease is associated with an increased risk for non-Hodgkin lymphoma, especially of T-cell type and primarily localized in the gut, however, the association does not represent a great enough risk to justify early mass screening for celiac disease.
Anemia of chronic disease and defective erythropoietin production in patients with celiac disease
TLDR
Suppression of intestinal inflammatory changes as a result of a gluten-free diet improves anemia by correcting iron and vitamin malabsorption as well as mechanisms contributing to anemia of chronic disease.
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