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Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease
TLDR
In patients with NAFLD, both gut permeability and the prevalence of SIBO correlated with the severity of steatosis but not with presence of NASH, and the increased permeability appears to be caused by disruption of intercellular tight junctions in the intestine.
European consensus conference on faecal microbiota transplantation in clinical practice
TLDR
This consensus report strongly recommends the implementation of FMT centres for the treatment of C. difficile infection as well as traces the guidelines of technicality, regulatory, administrative and laboratory requirements.
Methodology and Indications of H2‐Breath Testing in Gastrointestinal Diseases: the Rome Consensus Conference
TLDR
The final statements, graded according to the level of evidence and strength of recommendation, identify the indications for the use of H2-breath testing in the clinical practice and methods to be used for performing the tests.
Efficacy of Lactobacillus GG in maintaining remission of ulcerative colitis
Aminosalicylates are the mainstay of therapy to prevent relapse of quiescent ulcerative colitis. The rationale for using probiotics is based on the evidence implicating intestinal bacteria in the
Baclofen efficacy in reducing alcohol craving and intake: a preliminary double-blind randomized controlled study.
TLDR
Baclofen proved to be effective in inducing abstinence from alcohol and reducing alcohol craving and consumption in alcoholics and may represent a potentially useful drug in the treatment of alcohol-dependent patients and thus merits further investigations.
Ability of baclofen in reducing alcohol craving and intake: II--Preliminary clinical evidence.
TLDR
Preclinical evidence on the effect of short-term baclofen administration on craving for alcohol, ethanol intake, and abstinence from alcohol in alcoholic individuals is supported and the anticraving properties of the drug suggest a possible role of bacl ofen in the treatment of individuals with alcohol problems.
Effect of different probiotic preparations on anti-Helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study
TLDR
All the probiotics used were superior to placebo for side effect prevention, but were not associated with better compliance with antibiotic therapy.
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