Trypsinogen

Known as: Trypsinogen [Chemical/Ingredient] 
The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Genetic investigations have provided unique insight into the mechanism of chronic pancreatitis in humans and firmly established… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
We have developed a protocol to assemble in one step and one tube at least nine separate DNA fragments together into an acceptor… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Hereditary pancreatitis has been reported to be caused by 'gain-of-function' missense mutations in the cationic trypsinogen gene… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Autodigestion of the pancreas by its own prematurely activated digestive proteases is thought to be an important event in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS In pancreatitis, a key role has been attributed to the inappropriate conversion of trypsinogen to trypsin… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Supramaximal stimulation of the pancreas with the CCK analog caerulein causes acute edematous pancreatitis. In this model, active… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Freezing avoidance conferred by different types of antifreeze proteins in various polar and subpolar fishes represents a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS We recently identified a single R117H mutation in the cationic trypsinogen gene in several kindreds with an… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
BACKGROUND & AIMS One of the central, unresolved issues in the pathogenesis of acute pancreatitis is the uncertainty regarding… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Hereditary pancreatitis (HP) is a rare, early-onset genetic disorder characterized by epigastric pain and often more serious… (More)
Is this relevant?