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PRSS2 protein, human

Known as: trypsinogen 2 protein, human, trypsin 2 protein, human, protease, serine, 2 (trypsin 2) protein, human 
Trypsin-2 (247 aa, ~26 kDa) is encoded by the human PRSS2 gene. This protein is involved in the catabolism of proteins in the small intestine.
National Institutes of Health

Related topics

Related topics

11 relations
DigestionEnzyme GeneExtracellular SpaceHydrolysis

Broader (2)

TRYPSINTrypsinogen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
A loss of function polymorphism (G191R) of anionic trypsinogen (PRSS2) confers protection against chronic pancreatitis.
2006
2006
Low clinical penetrance of mannose-binding lectin-associated serine protease 2 deficiency.
Highly Cited
2001
Highly Cited
2001
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation
Proteolysis mediated by matrix metalloproteinases (MMPs) and serine proteinases is associated with cancer invasion and metastasis… 
1999
1999
Assignment1 of the gene encoding mannan-binding lectin-associated serine protease 2 (MASP2) to human chromosome 1p36.3→p36.2 by in situ hybridization and somatic cell hybrid analysis
The complement system is an important constituent of the innate immune defense. It can be activated via an immune complex… 
1999
1999
Origin and implication of the hereditary pancreatitis-associated N21I mutation in the cationic trypsinogen gene
Abstract. The N21I missense mutation in the cationic trypsinogen gene is the second most frequent mutation in hereditary… 
1988
1988
Translational control of anionic trypsinogen and amylase synthesis in rat pancreas in response to caerulein stimulation.
Infusion of rats with optimal doses of caerulein for up to 24 hr resulted in divergent changes in protein synthesis in the… 
Highly Cited
1979
Highly Cited
1979
Trypsinogen variants in pancreatic juice of healthy volunteers, chronic alcoholics, and patients with pancreatitis and cancer of the pancreas
Polyacrylamide gel electrophoresis of pure pancreatic juice from 14 healthy normal subjects, 11 chronic alcoholics without… 
1976
1976
Activation peptide of human trypsinogen 2
1974
1974
On bovine and porcine anionic trypsinogens.
1971
1971
Studies of an anionic trypsinogen and its active enzyme from porcine pancreas.
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