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The complete amino acid sequence of papain. Additions and corrections.
TLDR
Earlier tentative and incomplete version of this sequence has been corrected and shown to be in accord with the studies of Drenth et al. by x-ray crystallographic methods. Expand
Crystalline papain. I. Preparation, specificity, and activation.
Subtilisin Carlsberg. V. The complete sequence; comparison with subtilisin BPN'; evolutionary relationships.
TLDR
Within the subtilisins, there are a number of distinct repetitions of sequence; this suggests that the proteins may have evolved from shorter peptide chains by some process of extension of the sequence. Expand
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. I. Purification and molecular properties.
TLDR
Improved growth conditions were developed for normal strain 1A of Neurospora crassa in order to induce a high level of the NAD-specific glutamate dehydrogenase, and isophthalate was found to be a strong competitive inhibitor and an effective stabilizer of the enzyme. Expand
Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues.
TLDR
The derived peptides showed that tryptic hydrolysis was entirely limited to peptide bonds involving lysine residues, as shown both by two-dimensional peptide patterns and by isolation of the resulting peptides, indicating the stability of DHCH-arginyl residues permits isolation of labeled peptides. Expand
Studies on the ultraviolet difference spectra of proteins and polypeptides.
TLDR
The present paper represents an extension of the data previously presented in preliminary form, and an attempt to identify the chromophore(s) responsible for the 230 to 235-rnp peak, which was shown that alterations in native protein structure were associated with the appearance of a peak in the difference spectrum on comparison of the native with the denatured protein. Expand
Histones: structure and function.
Amino acid composition of crystalline carboxypeptidase.
Identification of functional arginine residues in ribonuclease A and lysozyme.
TLDR
A specific color reaction has been developed for the detection of N-7, N-8-(1,2-dihydroxycyclohex-1, 2-ylene)-L-arginine-containing peptides and changes in tryptic peptide patterns can also be utilized to identify the presence of modified arginine residues. Expand
Proteolytic activity of pituitary extracts.
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