Trimedoxime

Known as: Trimedoxime [Chemical/Ingredient], TMB-4, Pyridinium, 1,1'-(1,3-propanediyl)bis(4-(hydroxyimino)methyl)-, dibromide 
Cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.
National Institutes of Health

Papers overview

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2013
2013
K027 [1-(4-hydroxyiminomethylpyridinium)-3-(4-carbamoylpyridinium)-propane dibromide] is a promising new reactivator of… (More)
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2011
2011
The characterization of an economic and ease-to-use carbon paste acetylcholinesterase (AChE) based biosensor to determine the… (More)
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2009
2009
The capability of several oximes (HI-6, HLö7, MMB-4, TMB-4, carboxime, ICD 585, ICD 692, ICD 3805, and 2-PAM) to reactivate in… (More)
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2008
2008
The potency of newly developed monoxime bispyridinium compounds (K156, K203) in reactivating tabun-inhibited acetylcholinesterase… (More)
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2005
2005
The neurochemical effects of repeated postnatal exposure to chlorpyrifos (CPS) were studied in developing rats. Rats were gavaged… (More)
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2003
2003
A novel series of acetylcholinesterase (AChE) inhibitors of the bispyridinium type was synthesized and the inhibitory activity… (More)
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1996
1996
The reaction of human erythrocyte acetylcholinesterase (AChE) with a set of structurally related phosphoramidates was studied in… (More)
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1996
1996
Diethylphosphoryl conjugates of human acetylcholinesterase (AChE) and selected mutants, carrying amino acid replacements at the… (More)
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1986
1986
A study of the effects of bisquaternary pyridinium oximes on calcium-dependent potassium-evoked [3H]acetylcholine release from… (More)
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1981
1981
Soman is a highly toxic organophosphorus chemical warfare nerve agent which is characterized by (1) extremely rapid ageing of the… (More)
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