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Tricho-dento-osseous syndrome (disorder)

Known as: TDO SYNDROME, TDO, Tricho-dento-osseous syndrome 
 
National Institutes of Health

Related topics

Related topics

10 relations
Autosomal dominant inheritanceDLX3, 2-BP DEL, 560CTDLX3, 4-BP DEL, NT3198Frontal bossing
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Broader (3)

Craniofacial AbnormalitiesDental Enamel HypoplasiaHair Diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer
Exploding interest in immunometabolism as a source of new cancer therapeutics has been driven in large part by studies of… Expand
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Highly Cited
2012
Highly Cited
2012
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO1) is an important mechanism of peripheral immune tolerance… Expand
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Highly Cited
2012
Highly Cited
2012
IDO inhibits a tryptophan sufficiency signal that stimulates mTOR
Tryptophan catabolism by indoleamine 2,3-dioxygenase (IDO) alters inflammation and favors T-cell tolerance in cancer, but the… Expand
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Highly Cited
2012
Highly Cited
2012
Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibition.
Indoleamine 2,3-dioxygenase 1 (IDO1) is an important therapeutic target for the treatment of diseases such as cancer that involve… Expand
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Highly Cited
2011
Highly Cited
2011
The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease
Neuroactive metabolites of the kynurenine pathway (KP) of tryptophan degradation have been implicated in the pathophysiology of… Expand
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Highly Cited
2011
Highly Cited
2011
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance… Expand
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Highly Cited
2010
Highly Cited
2010
Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity.
Indoleamine 2,3-dioxygenase-1 (IDO1; IDO) mediates oxidative cleavage of tryptophan, an amino acid essential for cell… Expand
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Highly Cited
2009
Highly Cited
2009
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice
Although nutrients, including amino acids and their metabolites such as serotonin (5-HT), are strong modulators of anxiety… Expand
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Highly Cited
2007
Highly Cited
2007
Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice.
Indoleamine 2,3-dioxygenase (INDO) and tryptophan 2,3-dioxygenase (TDO) each catalyze the first step in the kynurenine pathway of… Expand
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Review
2006
Review
2006
Monitoring tryptophan metabolism in chronic immune activation.
The essential amino acid tryptophan is a constituent of proteins and is also a substrate for two important biosynthetic pathways… Expand
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