Translocation Breakpoint

The point on a chromosome where the normal DNA sequence is juxtaposed with DNA from another chromosome. Usually expressed as a band number… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2018
010203019722018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Chromosomal translocations arise from the misjoining of DNA breaks, but the identity of the DNA repair factors and activities… (More)
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Highly Cited
2001
Highly Cited
2001
Individuals affected with developmental disorders of speech and language have substantial difficulty acquiring expressive and/or… (More)
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Highly Cited
2000
Highly Cited
2000
The hallmark of chronic myeloid leukemia (CML) is the BCR-ABL fusion gene, which is usually formed as a result of the t(9;22… (More)
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Highly Cited
1997
Highly Cited
1997
Dysregulation of oncogenes by translocation to the IgH locus (14q32) is a seminal event in the pathogenesis of B-cell tumours1… (More)
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Highly Cited
1996
Highly Cited
1996
A 200-300 kb region of chromosome 3p14.2, including the fragile site locus FRA3B, is homozygously deleted in multiple tumor… (More)
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Highly Cited
1996
Highly Cited
1996
In multiple myeloma, karyotopic 14q32 translocations have been identified at a variable frequency (10-60% in different studies… (More)
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Highly Cited
1992
Highly Cited
1992
Some acute lymphocytic leukaemias, particularly those in young children, are associated with a t(4;11)(q21;q23) reciprocal… (More)
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Highly Cited
1990
Highly Cited
1990
Three new neurofibromatosis type 1 (NF1) mutations have been detected and characterized. Pulsed-field gel and Southern blot… (More)
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Highly Cited
1990
Highly Cited
1990
The gene (E2A) for enhancer binding transcription factors E12 and E47 maps to the t(1;19) chromosomal translocation breakpoint in… (More)
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Highly Cited
1984
Highly Cited
1984
We have identified and molecularly cloned 46 kb of human DNA from chromosome 22 using a probe specific for the Philadelphia (Ph… (More)
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