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Transcription Factor AP-1, human

Known as: AP1, JUN, v-jun Avian Sarcoma Virus 17 Oncogene Homolog 
Transcription factor AP-1 (331 aa, ~36 kDa) is encoded by the human JUN gene. This protein plays a role in transcriptional activation.
National Institutes of Health

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Related topics

48 relations
AP1 complexAP1 complex locationATM Signaling PathwayAgrin Pathway

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Transcription Factor AP-1

Papers overview

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2010
2010
Membrane association facilitates degradation and cleavage of the cyclin-dependent kinase 5 activators p35 and p39.
Cyclin-dependent kinase 5 (Cdk5) is activated by binding to its activators, p35 and p39. The level of Cdk5 activity is determined… 
2005
2005
Effect of If-D-Arabinofuranosylcytosine on Apoptosis and Differentiation in Human Monocytic Leukemia Cells ( U 937 ) Expressing a c-Jun Dominant-Negative Mutant Protein ( TAM 67 ) 1
The proto-oncogene c-jun encodes a component of the AP-I transcription-activating complex and has been implicated in the… 
2004
2004
Glucose Utilization Is Essential for Hypoxia-Inducible Factor 1α-Dependent Phosphorylation of c-Jun
ABSTRACT Hypoxia and anoxia are important microenvironmental stresses that contribute to pathological events such as solid-tumor… 
Highly Cited
1999
Highly Cited
1999
Cell-Extracellular Matrix Interactions Stimulate the AP-1 Transcription Factor in an Integrin-Linked Kinase- and Glycogen Synthase Kinase 3-Dependent Manner
ABSTRACT Integrin-mediated interactions of cells with components of the extracellular matrix regulate cell survival, cell… 
1996
1996
Selective activation of the proto-oncogene c-jun promoter by the transforming protein v-Rel.
The transcription factor v-Rel is a transforming protein of the reticuloendotheliosis virus. We found that v-Rel activates the… 
1996
1996
Overexpression of the proto‐oncogene C‐jun in association with low‐risk type specific human papillomavirus infection in condyloma acuminata
Infection with different types of human papillomavirus (HPV) is associated with neoplasia at different anatomic sites. The “low… 
1994
1994
Neuronal expression of Fos and Jun protein in the rat medulla and spinal cord after anoxic and hypercapnic stimulations
Highly Cited
1992
Highly Cited
1992
Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity.
The proto-oncogene c-jun encodes the major component of the transcription factor AP-1 and is thought to have important functions… 
Highly Cited
1991
Highly Cited
1991
The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells
The nuclear phosphoprotein c-Jun, encoded by the proto-oncogene c-jun, is a major component of the AP-1 complex. A potent… 
1991
1991
Aging and restriction of dietary calories increases insulin receptor mRNA, and aging increases glucocorticoid receptor mRNA in the liver of female C3B10RF1 mice.
We investigated the influence of age and a 20% or 52% reduction in dietary calories (caloric restriction) on expression of mRNA… 
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