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AP1 complex

Known as: AP-1 Complex, Enhancer-Binding Protein AP1, Activator Protein 1 Complex 
A dimeric complex of related bZIP JUN, FOS, MAF and ATF transcription factors that must dimerize in order to bind to AP1 recognition sites (TPA… Expand
National Institutes of Health

Related topics

Related topics

15 relations
AP1 complex locationCell NucleusFOSB protein, humanFOSL1 protein, human
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Papers overview

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Highly Cited
2009
Highly Cited
2009
JNK1-dependent PUMA Expression Contributes to Hepatocyte Lipoapoptosis*
Free fatty acids (FFA) induce hepatocyte lipoapoptosis by a c-Jun N-terminal kinase (JNK)-dependent mechanism. However, the… Expand
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Highly Cited
2008
Highly Cited
2008
Modulation of Antioxidant Defense in Aspergillus parasiticus Is Involved in Aflatoxin Biosynthesis: a Role for the ApyapA Gene
ABSTRACT Oxidative stress is recognized as a trigger of different metabolic events in all organisms. Various factors correlated… Expand
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Highly Cited
2004
Highly Cited
2004
Functional Characterization of OsMADS18, a Member of the AP1/SQUA Subfamily of MADS Box Genes1[w]
MADS box transcription factors controlling flower development have been isolated and studied in a wide variety of organisms… Expand
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Highly Cited
2001
Highly Cited
2001
Identification of a Novel Metabolite in the Degradation of Pyrene by Mycobacterium sp. Strain AP1: Actions of the Isolate on Two- and Three-Ring Polycyclic Aromatic Hydrocarbons
ABSTRACT Mycobacterium sp. strain AP1 grew with pyrene as a sole source of carbon and energy. The identification of metabolites… Expand
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Highly Cited
1999
Highly Cited
1999
Angiotensin II stimulates expression of transforming growth factor β receptor type II in cultured mouse proximal tubular cells
Tubulointerstitial fibrosis is a common end-point of many chronic renal diseases and contributes to the permanent loss of renal… Expand
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Highly Cited
1997
Highly Cited
1997
Transactivation through Ets and Ap1 transcription sites determines the expression of the tumor-suppressing gene maspin.
Tumor invasion and metastasis are processes poorly understood at the molecular level. Maspin is a serine protease inhibitor… Expand
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Highly Cited
1995
Highly Cited
1995
Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene.
Endothelin-1 (ET-1) is a 21-amino-acid vasoactive peptide initially characterized as a product of endothelial cells. Reporter… Expand
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Highly Cited
1992
Highly Cited
1992
Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element.
Deletion mutagenesis and transfection studies into hepatic (mouse hepatoma (Hepa-1) and human hepatoblastoma (Hep-G2)) and… Expand
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Highly Cited
1992
Highly Cited
1992
Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes.
The activity and epithelial tropism of the human papillomavirus type 18 P105 early promoter, which directs the synthesis of the… Expand
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Highly Cited
1987
Highly Cited
1987
Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry
Platelets may become activated in a number of clinical disorders and participate in thrombus formation. We developed a direct… Expand
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