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Transcription Elongation

The RNA polymerase moves along the DNA template, adding nucleotides to the growing RNA chain in accordance with the sequence of the template or… 
National Institutes of Health

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36 relations
CD3EAP protein, humanCDK9 geneCDK9 protein, humanCDK9 wt Allele

Papers overview

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Highly Cited
2005
Highly Cited
2005
Transcription-dependent Association of Multiple Positive Transcription Elongation Factor Units to a HEXIM Multimer*
The positive transcription elongation factor (P-TEFb) comprises a kinase, CDK9, and a Cyclin T1 or T2. Its activity is inhibited… 
Highly Cited
2004
Highly Cited
2004
MAZ Elements Alter Transcription Elongation and Silencing of the Fibroblast Growth Factor Receptor 2 Exon IIIb*
The fibroblast growth factor receptor 2 (FGFR2) gene exons IIIb and IIIc are alternatively spliced in a mutually exclusive and… 
Highly Cited
2002
Highly Cited
2002
MCEF, the Newest Member of the AF4 Family of Transcription Factors Involved in Leukemia, Is a Positive Transcription Elongation Factor-b-Associated Protein
Positive transcription elongation factor-b (P-TEFb) contains CDK9 and cyclin T1. P-TEFb was affinity purified from a stably… 
Highly Cited
2001
Highly Cited
2001
Hpr1 Is Preferentially Required for Transcription of Either Long or G+C-Rich DNA Sequences in Saccharomyces cerevisiae
ABSTRACT Hpr1 forms, together with Tho2, Mft1, and Thp2, the THO complex, which controls transcription elongation and genome… 
Review
1999
Review
1999
Transcription elongation and human disease.
Eukaryotic mRNA synthesis is catalyzed by multisubunit RNA polymerase II and proceeds through multiple stages referred to as… 
Highly Cited
1998
Highly Cited
1998
A Novel Nuclear Import Pathway for the Transcription Factor TFIIS
We have identified a novel pathway for protein import into the nucleus. We have shown that the previously identified but… 
Highly Cited
1996
Highly Cited
1996
Efficient inhibition of transcription elongation in vitro by oligonucleotide phosphoramidates targeted to proviral HIV DNA.
Triplex-forming oligophosphoramidates containing thymines and cytosines or 5-methyl cytosines (5' T4CT4C6T 3') bind strongly to a… 
Highly Cited
1994
Highly Cited
1994
Discontinuous mechanism of transcription elongation.
During transcription elongation, three flexibly connected parts of RNA polymerase of Escherichia coli advance along the template… 
Highly Cited
1990
Highly Cited
1990
The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles.
Aberrant c-myc expression patterns occur in human Burkitt's lymphoma cells, which consistently exhibit c-myc chromosomal… 
Highly Cited
1985
Highly Cited
1985
Studies on transcription of 3'-extended templates by mammalian RNA polymerase II. Parameters that affect the initiation and elongation reactions.
Addition of short sequences of dCMP residues to the 3'-OH end of duplex linear DNAs allows rapid and efficient transcription to… 
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