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CDK9 protein, human

Known as: CDK-9 protein, human, Tat-Associated Kinase Complex Catalytic Subunit, C-2K 
Cyclin-dependent kinase 9 (372 aa, ~43 kDa) is encoded by the human CDK9 gene. This protein plays a role in the positive regulation of… 
National Institutes of Health

Related topics

Related topics

23 relations
CDK12 protein, humanCDK2 protein, humanCDK3 protein, humanCDK4 protein, human

Broader (1)

Cyclin-Dependent Kinase 9

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Transient induction of Cdk9 in the early stage of differentiation is critical for myogenesis
Cdk9 is a serine‐threonine protein kinase that has been recognized as a regulator of cardiac differentiation. Recently, we have… 
2017
2017
miR‐206 inhibits the growth of hepatocellular carcinoma cells via targeting CDK9
miR‐206 plays an important role in regulating the growth of multiple cancer cells. Cyclin‐dependent kinase 9 (CDK9) stimulates… 
2016
2016
Molecular principle of the cyclin-dependent kinase selectivity of 4-(thiazol-5-yl)-2-(phenylamino) pyrimidine-5-carbonitrile derivatives revealed by molecular modeling studies.
Due to the high sequence identity of the binding pockets of cyclin-dependent kinases (CDKs), designing highly selective… 
2014
2014
Genetic Analysis of the Structure and Function of 7SK Small Nuclear Ribonucleoprotein (snRNP) in Cells*
Background: HEXIM1 and LaRP7 bind to 7SK snRNA. Results: HEXIM1 and LaRP7 activation domain chimeras activated plasmid targets… 
Review
2011
Review
2011
Novel, selective CDK9 inhibitors for the treatment of HIV infection.
Cyclin Dependent Kinases (CDKs) are important regulators of cell cycle and gene expression. Since an up-to-date review about the… 
Review
2008
Review
2008
RNA‐driven cyclin‐dependent kinase regulation: When CDK9/cyclin T subunits of P‐TEFb meet their ribonucleoprotein partners
The positive transcription elongation factor (P‐TEFb) consists of CDK9, a cyclin‐dependent kinase and its cyclin T partner. It is… 
2006
2006
HIV-1 Tat interaction with cyclin T1 represses mannose receptor and the bone morphogenetic protein receptor-2 transcription.
Review
2004
Review
2004
HIV-1 infection and regulation of Tat function in macrophages.
Highly Cited
2002
Highly Cited
2002
Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol.
Highly Cited
2001
Highly Cited
2001
The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9.
We identify and characterize several phosphorylated forms of the hSpt5 subunit of the DRB sensitivity-inducing factor (DSIF). A… 
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