CDK9 protein, human

Known as: CDK-9 protein, human, Tat-Associated Kinase Complex Catalytic Subunit, C-2K 
Cyclin-dependent kinase 9 (372 aa, ~43 kDa) is encoded by the human CDK9 gene. This protein plays a role in the positive regulation of… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
CDK9 is a protein in constant development in cancer therapy. Herein we present an overview of the enzyme as a target for cancer… (More)
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Highly Cited
2009
Highly Cited
2009
TGF-beta and BMP receptor kinases activate Smad transcription factors by C-terminal phosphorylation. We have identified a… (More)
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Highly Cited
2008
Highly Cited
2008
The positive transcription elongation factor b (P-TEFb) (CDK9/cyclin T (CycT)) promotes mRNA transcriptional elongation through… (More)
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Highly Cited
2004
Highly Cited
2004
The positive transcription elongation factor b (P-TEFb) plays a pivotal role in productive elongation of nascent RNA molecules by… (More)
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Highly Cited
2003
Highly Cited
2003
Positive transcription elongation factor b (P-TEFb) comprises a cyclin (T1 or T2) and a kinase, cyclin-dependent kinase 9 (CDK9… (More)
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Highly Cited
2002
Highly Cited
2002
Stimulation of transcriptional elongation by the human immunodeficiency virus type 1 Tat protein is mediated by CDK9, a kinase… (More)
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Highly Cited
2001
Highly Cited
2001
The transcription of eukaryotic protein-coding genes involves complex regulation of RNA polymerase (Pol) II activity in response… (More)
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Highly Cited
2000
Highly Cited
2000
Tat stimulates human immunodeficiency virus type 1 (HIV-1) transcriptional elongation by recruitment of carboxyl-terminal domain… (More)
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Highly Cited
1999
Highly Cited
1999
Important progress in the understanding of elongation control by RNA polymerase II (RNAPII) has come from the recent… (More)
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Highly Cited
1998
Highly Cited
1998
HIV-1 Tat activates transcription through binding to human cyclin T1, a regulatory subunit of the TAK/P-TEFb CTD kinase complex… (More)
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