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Toyocamycin

Known as: 7H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-beta-D-ribofuranosyl-, Toyocamycin [Chemical/Ingredient], Deazacyanoadenosine 
4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The IRE1α-XBP1 pathway, a key component of the endoplasmic reticulum (ER) stress response, is considered to be a critical… Expand
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Highly Cited
2008
Highly Cited
2008
Pyrrolopyrimidine nucleosides analogs, collectively referred to as deazapurines, are an important class of structurally diverse… Expand
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Highly Cited
1989
Highly Cited
1989
A number of 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3d-d]pyrimidine derivatives that are structurally related to toyocamycin… Expand
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1989
1989
A number of 7-[(2-hydroxyethoxy)methyl]pyrrolo[2,3-d]pyrimidine derivatives related to the nucleoside antibiotics toyocamycin and… Expand
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Highly Cited
1987
Highly Cited
1987
Treatment of 7-amino-3-beta-D-ribofuranosylpyrazolo[4,3-d]pyrimidine (formycin) with alpha-acetoxyisobutyryl bromide followed by… Expand
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Review
1982
Review
1982
  • J. Phillis, P. Wu
  • Comparative biochemistry and physiology. C…
  • 1982
  • Corpus ID: 23155221
1. Adenosine and its analogs depress the firing of neurons in various brain regions. The primary mode of action of adenosine in… Expand
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Highly Cited
1978
Highly Cited
1978
The pyrrolopyrimidine nucleosides toyocamycin and tubercidin show several unique features of growth inhibition in Chinese hamster… Expand
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Highly Cited
1975
Highly Cited
1975
Abstract Adenosine deaminase (adenosine aminohydrolase, EC 3.5.4.4) has been purified about 3000-fold from human erythrocytes… Expand
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Highly Cited
1969
Highly Cited
1969
Abstract Small concentrations of the adenosine analogue toyocamycin inhibit the maturation of rRNA, but permit the synthesis of… Expand
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Highly Cited
1966
Highly Cited
1966
  • S. Frederiksen
  • Archives of biochemistry and biophysics
  • 1966
  • Corpus ID: 41436094
Abstract A purified adenosine deaminase from calf intestine was investigated with respect to its substrate specificity. Kinetic… Expand
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