Toyocamycin

Known as: 7H-Pyrrolo(2,3-d)pyrimidine-5-carbonitrile, 4-amino-7-beta-D-ribofuranosyl-, Toyocamycin [Chemical/Ingredient], Deazacyanoadenosine 
4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an… (More)
National Institutes of Health

Papers overview

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2012
2012
The IRE1α-XBP1 pathway, a key component of the endoplasmic reticulum (ER) stress response, is considered to be a critical… (More)
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2012
2012
Rio1 kinase is an essential ribosome-processing factor required for proper maturation of 40 S ribosomal subunit. Although its… (More)
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2010
2010
This study investigates the susceptibility of a clinically metronidazole (Mz)-resistant isolate of Trichomonas vaginalis to… (More)
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2009
2009
The auxins, plant hormones, play a crucial role in many aspects of plant development by regulating cell division, elongation and… (More)
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2008
2008
Pyrrolopyrimidine nucleosides analogs, collectively referred to as deazapurines, are an important class of structurally diverse… (More)
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2002
2002
We constructed an assay system of a luciferase reporter with p16/lNK4a gene transcriptional regulatory domain to identify p16… (More)
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1997
1997
Toyocamycin is an antitumor antibiotic which has a pyrrolo[2,3-D]pyrimidine aglycone with a -CN substituent on the 5-carbon… (More)
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1990
1990
We have screened toyocamycin as an inhibitor of phosphatidylinositol kinase. It inhibited the enzyme of A431 cell membrane with… (More)
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1974
1974
The purine nucleoside analogs, toyocamycin, tubercidin, and 6-thioguanosine, all inhibit ribosomal RNA maturation in cultured… (More)
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1969
1969
The antibiotic toyocamycin (TCM) selectively inhibits the synthesis of ribosomal RNA in different mammalian cells by suppressing… (More)
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