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Toxiferine

Known as: Toxiferine I, 2,2',16,16'-tetradehydro-16,16',17,17'-tetrahydro-, Toxiferine [Chemical/Ingredient] 
A curare alkaloid that is a very potent competitive nicotinic antagonist at the neuromuscular junction.
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionagonistsanalogs & derivatives

Broader (2)

Neuromuscular Nondepolarizing AgentsNicotinic Antagonists

Narrower (1)

bisnordihydrotoxiferine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Pharmacological characteristics and binding modes of caracurine V analogues and related compounds at the neuronal alpha7 nicotinic acetylcholine receptor.
The pharmacological properties of bisquaternary caracurine V, iso-caracurine V, and pyrazino[1,2-a;4,5-a']diindole analogues and… 
2004
2004
Bisquaternary caracurine V and iso-caracurine V salts as ligands for the muscle type of nicotinic acetylcholine receptors: SAR and QSAR studies.
2004
2004
Localization of 14C-pancuronium by histo- and wholebody-autoradiography in normal and pregnant mice
Summary14C-Pancuronium is distributed in the aqueous phase of the mouse within 10 min of its intravenous injection. Excretion… 
1973
1973
Effects of gallamine on plasma cortisol and catecholamine levels in man
SummaryEffects of gallamine on plasma cortisol and catecholamine concentrations were studied in ten elective surgical patients. A… 
1969
1969
The strychnine‐like action of curare and related compounds on the somatosensory evoked response of the rat cortex
1 . Drugs were applied to the cerebral cortex of rats anaesthetized with pentobarbitone and changes measured in the somatosensory… 
1962
1962
EXPERIMENTAL AND CLINICAL EXPERIENCES WITH A NEW MUSCLE RELAXANT Ro 4–3816, DIALLYL‐NOR‐TOXIFERINE
Ro 4–3816 (Diallyl‐nor‐toxiferin) ist ein neues nicht depolarisierendes Muskelerschlaffungsmittel. Dieses Derivat des Alkaloids… 
1962
1962
Revised distinction between direct and indirect response of electroplax.
1962
1962
POTENCY AND REVERSIBILITY BY PROSTIGMINE OF Ro 4–3816 AND d‐TUBOCURARINE: A “Blind” Study
Using a blind technique, the muscular relaxation produced by diallyl‐nortoxiferine (Ro 4–3816) during tracheal intubation and in… 
1961
1961
Experimental and clinical experience with toxiferine (alkaloid of calabash curare)
  • R. FreyR. Seeger
  • Canadian Anaesthetists' Society journal
  • 1961
  • Corpus ID: 27071687
SummaryThe Calabash alkaioid Toxiferine is, the most potent and long-acting relaxant of the curare group available to the clinic… 
1961
1961
THE USE OF TOXIFERINE FOR THE PRODUCTION OF SURGICAL RELAXATION
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