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Toll-Like Receptor 3

Known as: Receptor, TLR3, Toll Like Receptor 3, TLR3 Receptor 
A pattern recognition receptor that binds DOUBLE-STRANDED RNA. It mediates cellular responses to certain viral pathogens.
National Institutes of Health

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TLR3 protein, human

Papers overview

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2015
2015
Activation of Toll like receptor 3 induces spermatogonial stem cell apoptosis
Germ cell apoptosis may be associated with the male infertility. The pathogenesis is to be further understood. Viral infection is… 
2014
2014
Quiescent Hepatic Stellate Cells Functionally Contribute to the Hepatic Innate Immune Response via TLR3
Toll-like Receptor 3 (TLR3) is a pathogen pattern recognition receptor that plays a key role in innate immunity. TLR3 signalling… 
2013
2013
Depletion of the 26S Proteasome Adaptor Ecm29 Increases Toll-Like Receptor 3 Signaling
Responses to viral infection involve both proteasomal and autophagy-mediated degradation events. Ecm Proteasomes Inhibit… 
2012
2012
Molecular cloning, characterization, and expression analysis of the Muscovy duck Toll-like receptor 3 (MdTLR3) gene.
Toll-like receptor 3 (TLR3) is an important membrane-bound receptor for recognizing double-stranded RNA in innate immunity. In… 
2012
2012
Molecular cloning , characterization , and expression analysis of the Muscovy duck Toll-like receptor 3 ( MdTLR 3 ) gene
Toll-like receptor 3 (TLR3) is an important membrane-bound receptor for recognizing doublestranded RNA in innate immunity. In… 
2011
2011
Toll like receptor 3 expression as a novel predictor of response to treatment in chronic hepatitis C virus patients
Abstract Purpose. This work was carried out to study the level of pretreatment hepatic expression of Toll like receptor 3 (TLR3… 
Review
2010
Review
2010
Toll-Like Receptor 3 in Liver Diseases
Toll-like receptor 3 (TLR3) is a member of the TLR family that can recognize double-stranded RNA (dsRNA), playing an important… 
Review
2010
Review
2010
[Research and development for treating devastating corneal diseases].
In order to develop new therapeutic modalities for corneal diseases, it is essential to combine cutting-edge translational… 
2006
2006
Toll like receptor 3 expression and efficacy of adjuvant treatment with polyadenylic-polyuridylic acid in patients with axillary node positive breast cancer: Results from two randomized trials.
10563 Background: Toll like receptor 3 (TLR3) are transmembrane receptors involved in the cellular response to danger signal and… 
2004
2004
Targeting Toll like receptor 3 by double stranded RNA in breast cancer: Results from in vitro studies and randomized trial.
9619 Background : Toll like receptor 3 (TLR3) is known to be expressed by myeloid dendritic cells (DC) and to induce their… 
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