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TLR3 gene

Known as: CD283, TOLL-LIKE RECEPTOR 3, TLR3 
This gene is involved in innate antiviral responses.
National Institutes of Health

Related topics

Related topics

8 relations
Antiviral ResponseImmune responseLigand BindingRNA Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Glycogen Synthase Kinase 3β Regulates Antiviral Responses of TLR3 via TRAF2–Src Axis
Key Points GSK3β interacts with Src tyrosine kinase. Src positively regulates antiviral immune response. Src undergoes K63-linked… 
2014
2014
Exonic single nucleotide polymorphisms within TLR3 associated with infant responses to serogroup C meningococcal conjugate vaccine.
Highly Cited
2012
Highly Cited
2012
IFN-λ3 Inhibits HIV Infection of Macrophages through the JAK-STAT Pathway
Background Interferon lambda 3 (IFN-λ3) is a newly identified cytokine with antiviral activity, and its single nucleotide… 
2012
2012
Expression of BMP2, TLR3, TLR4 and COX2 in colorectal polyps, adenoma and adenocarcinoma.
The initiation and development of colorectal cancer is closely associated with the malignant transformation of… 
2010
2010
TLR3-dependent upregulation of RIG-I leads to enhanced cytokine production from cells infected with the parainfluenza virus SV5.
2010
2010
Gene-expression analysis of polyI:C-stimulated primary human conjunctival epithelial cells
Background The authors previously reported that human ocular surface epithelium expressed TLR3 and that its ligand polyI:C… 
2009
2009
Costunolide inhibits cyclooxygenase-2 expression induced by toll-like receptor 3 or 4 agonist
Toll-like receptors (TLRs) play an important role in the induction of innate immune responses recognizing conserved microbial… 
2009
2009
Inhibitory effects of 2,6-di-O-methyl-alpha-cyclodextrin on poly I:C signaling in macrophages.
2008
2008
Role of TLR3 in the immunogenicity of replicon plasmid-based vaccines
Replicon plasmids encoding an alphavirus RNA replicase constitute an alternative to conventional DNA plasmids with promise for… 
Highly Cited
2004
Highly Cited
2004
Exogenous siRNA Mediates Sequence-Independent Gene Suppression by Signaling through Toll-Like Receptor 3
RNA interference (RNAi) is a powerful method that specifically suppresses gene expression in a sequence-dependent manner whose… 
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