TLR3 gene

Known as: CD283, TOLL-LIKE RECEPTOR 3, TLR3 
This gene is involved in innate antiviral responses.
National Institutes of Health

Papers overview

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2014
2014
Chikungunya virus (CHIKV) has received global attention due to the series of large-scale outbreaks in different parts of the… (More)
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2013
2013
TLR3 belongs to the family of intracellular TLRs that recognize nucleic acids. Endolysosomal localization and cleavage of… (More)
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2010
2010
TLR3 recognizes dsRNAs and is considered of key importance to antiviral host-defense responses. TLR3 also triggers… (More)
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2010
2010
Despite its potential for involvement in viral immunity, little evidence links TLR3 to adaptive antiviral responses. Here we show… (More)
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2009
2009
Replicon plasmids encoding an alphavirus RNA replicase constitute an alternative to conventional DNA plasmids with promise for… (More)
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Highly Cited
2008
Highly Cited
2008
Clinical trials of small interfering RNA (siRNA) targeting vascular endothelial growth factor-A (VEGFA) or its receptor VEGFR1… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Toll-like receptors (TLRs) are essential components of the immune response to fungal pathogens. We examined the role… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Age-related macular degeneration is the most common cause of irreversible visual impairment in the developed world… (More)
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Highly Cited
2006
Highly Cited
2006
Complexing TLR9 agonists such as plasmid DNA to cationic liposomes markedly potentiates their ability to activate innate immunity… (More)
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Highly Cited
2005
Highly Cited
2005
Poly(I:C), a synthetic double-stranded RNA polymer and a TLR3 agonist, can be used as a vaccine adjuvant to enhance adaptive… (More)
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