Toll-Like Receptor 1, human

Analysis of the genomes of two distantly related bird species, chicken and zebra finch (divergence of about 100 million years… (More)

Toll-like receptor 2 (TLR2) initiates potent immune responses by recognizing diacylated and triacylated lipopeptides. Its ligand… (More)

T he financial market turmoil in 2007 and 2008 has led to the most severe financial crisis since the Great Depression and… (More)

It has demonstrated that the recognition of triacylated lipopeptides by Toll-like receptor (TLR) 2 requires TLR1 as a coreceptor… (More)

BACKGROUND Rapid innate immune defences against infection involve the recognition of invading pathogens by specific pattern… (More)

The toll-like family of receptors (TLR) is an ancient pattern recognition receptor family, conserved from insects to mammals. We… (More)

The Toll-like receptor (TLR) family acts as pattern recognition receptors for pathogen-specific molecular patterns (PAMPs). TLR2… (More)

Mammalian Toll-like receptors (TLRs) function as sensors of infection and induce the activation of innate and adaptive immune… (More)

Toll-like receptors (TLRs) recognize specific molecular patterns present only in micro-organisms and thereby activate innate… (More)

Members of the Toll-like receptor (TLR) family are components of the mammalian anti-microbial response, signaling with a domain… (More)