Toll-Like Receptor 1, human

Known as: CD281 Antigen, Toll-Like Receptor 1, TLR1 
Toll-like receptor 1 (786 aa, ~90 kDa) is encoded by the human TLR1 gene. This protein plays a role in antimicrobial immune responses.
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Analysis of the genomes of two distantly related bird species, chicken and zebra finch (divergence of about 100 million years… (More)
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Highly Cited
2009
Highly Cited
2009
Toll-like receptor 2 (TLR2) initiates potent immune responses by recognizing diacylated and triacylated lipopeptides. Its ligand… (More)
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Highly Cited
2008
Highly Cited
2008
T he financial market turmoil in 2007 and 2008 has led to the most severe financial crisis since the Great Depression and… (More)
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Highly Cited
2006
Highly Cited
2006
It has demonstrated that the recognition of triacylated lipopeptides by Toll-like receptor (TLR) 2 requires TLR1 as a coreceptor… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Rapid innate immune defences against infection involve the recognition of invading pathogens by specific pattern… (More)
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Highly Cited
2004
Highly Cited
2004
The toll-like family of receptors (TLR) is an ancient pattern recognition receptor family, conserved from insects to mammals. We… (More)
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Highly Cited
2002
Highly Cited
2002
The Toll-like receptor (TLR) family acts as pattern recognition receptors for pathogen-specific molecular patterns (PAMPs). TLR2… (More)
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Highly Cited
2002
Highly Cited
2002
Mammalian Toll-like receptors (TLRs) function as sensors of infection and induce the activation of innate and adaptive immune… (More)
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Highly Cited
2002
Highly Cited
2002
Toll-like receptors (TLRs) recognize specific molecular patterns present only in micro-organisms and thereby activate innate… (More)
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Highly Cited
2000
Highly Cited
2000
Members of the Toll-like receptor (TLR) family are components of the mammalian anti-microbial response, signaling with a domain… (More)
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