FAQ

Tissue Inhibitor of Metalloproteinases

Known as: Proteins, TIMP, TIMP Proteins, TIMP 
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role… (More)

Topic mentions per year

Topic mentions per year

1981-2018
010203019812018

Related topics

Related topics

21 relations
Collagenase InhibitorEnzyme InhibitionGenes, RegulatorIn Blood
(More)

Broader (3)

GlycoproteinsMatrix Metalloproteinase InhibitorsProtease Inhibitors

Narrower (3)

TIMP1 protein, humanTissue-Inhibitor of Metalloproteinase-1tissue inhibitor of metalloproteinase 4

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Tissue Inhibitor of Metalloproteinases
physiological aspects
agonists
Glycoproteins
Protease Inhibitors
TIMP1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer
Circulating tumor cells (CTCs) reflect aggressive tumor behavior by hematogenous tumor cell dissemination. The tissue inhibitor… (More)
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2009
2009
Dynamic changes in matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 levels during wound healing in diabetic rats.
BACKGROUND We investigated the mechanism of delayed would healing caused by diabetes and measured the dynamic changes in matrix… (More)
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Highly Cited
2007
Highly Cited
2007
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17.
Cleavage and release (shedding) of membrane proteins is a critical regulatory step in many normal and pathological processes… (More)
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2007
2007
Elevated matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 in obese children and adolescents.
Matrix metalloproteinases (MMPs) have been implicated in the atherosclerotic process and risk factors for the disease such as… (More)
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Highly Cited
2005
Highly Cited
2005
Smooth muscle cell matrix metalloproteinases in idiopathic pulmonary arterial hypertension.
Pulmonary arterial hypertension (PAH) results from persistent vasoconstriction, smooth muscle growth and extracellular matrix… (More)
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Highly Cited
2004
Highly Cited
2004
Atrial extracellular matrix remodeling and the maintenance of atrial fibrillation.
BACKGROUND Remodeling occurs in both ventricle and atrium in dilated cardiomyopathy and heart failure. However, the alteration of… (More)
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2003
2003
Systemic arterial expression of matrix metalloproteinases 2 and 9 in acute Kawasaki disease.
OBJECTIVE Coronary artery aneurysms are the major complication of Kawasaki disease (KD). Matrix metalloproteinases (MMPs… (More)
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Highly Cited
2001
Highly Cited
2001
Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization.
BACKGROUND The clinical benefits of lipid lowering with statins are attributed to changes in plaque composition leading to lesion… (More)
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2001
2001
Matrix metalloproteinase (MMP)-2, MMP-7, and tissue inhibitor of metalloproteinase-1 are closely related to the fibroproliferative process in the liver during chronic hepatitis C.
BACKGROUND/AIMS To study whether expression of matrix metalloproteinases and their inhibitors correlate with ongoing fibrogenesis… (More)
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Highly Cited
2000
Highly Cited
2000
Lipoxin A4 inhibits IL-1 beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases.
Lipoxins are a novel class of endogenous eicosanoid mediators that potently inhibit inflammatory events by signaling via specific… (More)
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