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Tissue Inhibitor of Metalloproteinases

Known as: Proteins, TIMP, TIMP Proteins, TIMP 
A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Macrophages and inflammation play a beneficial role during wound repair with macrophages regulating a wide range of processes… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE The mechanisms contributing to ascending thoracic aortic aneurysms associated with bicuspid aortic valves may differ… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate the effects of aging on left ventricular (LV) geometry, collagen levels, matrix metalloproteinase (MMP) and… Expand
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Highly Cited
2001
Highly Cited
2001
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disorder characterized by fibroblast proliferation and extracellular matrix… Expand
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Highly Cited
1998
Highly Cited
1998
We have used adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinase (TIMP)-1, -2, and -3 to examine their… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Abdominal aortic aneurysms (AAAs) are characterized by degradation of collagen and elastin resulting from increases in… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS Tissue inhibitors of metalloproteinases may contribute to liver fibrosis by preventing remodeling of fibrillar… Expand
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Highly Cited
1994
Highly Cited
1994
Matrix proteases play a critical role in cell invasion and migration, including the process of angiogenesis. The ability of… Expand
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Highly Cited
1989
Highly Cited
1989
Human melanoma cells secret a 21-kDa protein, termed CSC-21K, which binds with 1:1 molar stoichiometry to the matrix… Expand
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Highly Cited
1985
Highly Cited
1985
Collagen fibres form the stable architecture of connective tissues and their breakdown is a key irreversible step in many… Expand
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