Tissue-Inhibitor of Metalloproteinase-1

Known as: TIMP-1, Tissue Inhibitor of Metalloproteinase-1, Metalloproteinase-1 Tissue Inhibitor 
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of… (More)
National Institutes of Health

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Highly Cited
2005
Highly Cited
2005
BACKGROUND Alterations in the balance of matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) are… (More)
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Highly Cited
2005
Highly Cited
2005
Tissue inhibitors of metalloproteinases (TIMPs) inhibit matrix metalloproteinases and some members of a disintegrin and… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE In the present study, we investigated the association between tumor tissue levels of tissue inhibitor of… (More)
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Highly Cited
2002
Highly Cited
2002
Destruction of lung elastin is critical for development of emphysema associated with chronic obstructive pulmonary disease (COPD… (More)
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Highly Cited
2002
Highly Cited
2002
It has been suggested that the tissue inhibitor of metalloproteinases-1 (TIMP-1) is involved in spontaneous resolution of liver… (More)
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Highly Cited
2002
Highly Cited
2002
The purpose of this study was to examine the role of interstitial collagenases, members of the family of matrix… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND AND PURPOSE Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade the extracellular matrix… (More)
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Highly Cited
1996
Highly Cited
1996
Peroxynitrite (ONOO-) has recently been implicated in connective tissue destruction in vivo. We have studied the effect of ONOO… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND & AIMS Tissue inhibitors of metalloproteinases may contribute to liver fibrosis by preventing remodeling of fibrillar… (More)
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