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Exenatide versus glibenclamide in patients with diabetes.
- G. Derosa, P. Maffioli, +9 authors A. Cicero
- Diabetes technology & therapeutics
- 12 February 2010
BACKGROUND Incretin-based therapies have provided additional options for the treatment of type 2 diabetes mellitus. The aim of our study was to evaluate the effects of exenatide compared to… Expand
Metabolic effects of pioglitazone and rosiglitazone in patients with diabetes and metabolic syndrome treated with glimepiride: a twelve-month, multicenter, double-blind, randomized, controlled,…
BACKGROUND Glimepiride is approved as monotherapy and in combination with metformin or with insulin, whereas the combination of glimepiride with other antihyperglycemic drugs is under investigation.… Expand
Evaluation of metalloproteinase 2 and 9 levels and their inhibitors in diabetic and healthy subjects.
OBJECTIVES We hypothesized that molecules active in vascular remodeling (i.e. MMPs and their TIMPs) could be modified in diabetic patients, as indirect markers of the diabetes related generalized… Expand
Sulfonylureas and their use in clinical practice
Many anti-diabetic drugs with different mechanisms of action are now available for treatment of type 2 diabetes mellitus. Sulfonylureas have been extensively used for treatment of type 2 diabetes for… Expand
α-Glucosidase inhibitors and their use in clinical practice
Post-prandial hyperglycemia still remains a problem in the management of type 2 diabetes mellitus. Of all available anti-diabetic drugs, α-glucosidase inhibitors seem to be the most effective in… Expand
Psyllium improves dyslipidaemia, hyperglycaemia and hypertension, while guar gum reduces body weight more rapidly in patients affected by metabolic syndrome following an AHA Step 2 diet
The aim of this study was to comparatively evaluate the long-term effects of psyllium husk and guar gum supplementation on metabolic syndrome (MS) components. We randomised 141 MS patients to soluble… Expand
Matrix metalloproteinase-2 and -9 levels in obese patients.
- G. Derosa, I. Ferrari, +8 authors A. Cicero
- Biology, Medicine
- Endothelium : journal of endothelial cell…
- 1 July 2008
The data reported in literature revealed a novel function for matrix metalloproteinases (MMPs) as modulators of adipogenesis. However, their expression profile and role in the cellular… Expand
Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind,…
- G. Derosa, P. Ragonesi, A. Mugellini, L. Ciccarelli, Roberto Fogari
- Hypertension research : official journal of the…
- 1 July 2004
We evaluated the antihypertensive activity, glucose homeostasis and plasma lipid profile in patients with mild hypertension and type 2 diabetes mellitus treated by diet and exercise, and not in… Expand
Anti-obesity drugs: a review about their effects and their safety
Introduction: Amphetamines, rimonabant and sibutramine licenses as anti-obesity drugs have been withdrawn because of their adverse effects. In fact, orlistat is the only available long-term treatment… Expand
Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials.
- G. Derosa, P. Maffioli, L. E. Simental-Mendía, S. Bo, A. Sahebkar
- Pharmacological research
- 1 September 2016
The aim of this meta-analysis was to evaluate the efficacy of curcuminoids supplementation on circulating concentrations of IL-6 in randomized controlled trials (RCTs). The search included… Expand