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Tirazone

National Institutes of Health

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SR 4233

Broader (1)

tirapazamine

Papers overview

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Highly Cited
2001
Highly Cited
2001
Metabolism of tirapazamine by multiple reductases in the nucleus.
1999
1999
DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine.
Tirapazamine (TPZ) [3-amino-1,2,4-benzotriazine 1,4-dioxide, SR4233, WIN 59075, and Tirazone] is a novel anticancer drug that is… 
1999
1999
Reaction of the hypoxia-selective antitumor agent tirapazamine with a C1'-radical in single-stranded and double-stranded DNA: the drug and its metabolites can serve as surrogates for molecular oxygen…
The compound 3-amino-1,2,4-benzotriazine 1,4-dioxide (1, tirapazamine; also known as SR4233, WIN 59075, and tirazone) is a… 
Review
1998
Review
1998
Tirapazamine: laboratory data relevant to clinical activity.
Tirapazamine (TPZ, SR 4233, WIN 59075, 3-amino-1,2,4-benzotriazine 1,4-dioxide, Tirazone) is the lead compound in the… 
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