Tiapamil
National Institutes of Health
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The inhibitory effect of the phenylalkylamine-type Ca2+-entry blocker, tiapamil, on the fast Na+ inward current was investigated…
Calcium antagonists are an important new modality in cardiovascular therapy. Tiapamil, a congener of verapamil, is undergoing…
The investigation was designed to test whether nicardipine and tiapamil interact with digoxin, resulting in increased plasma…
The main pathways of biotransformation of tiapamil and basic pharmacokinetic information on the drug are presented and compared…
We studied the hemodynamic effects of the new calcium antagonist tiapamil (Ro 11–1781) in anesthetized open-chest dogs and…
The results obtained in a variety of isolated organ preparations characterize tiapamil as a calcium antagonist or calcium entry…
The antiarrhythmic effects of tiapamil were investigated in 48 patients, mean age 54, with acute myocardial infarction and…
We studied the effects of tiapamil during myocardial infarction in the anaesthetized baboon. 10 animals received placebo and 8…
The antihypertensive effects of intravenously and orally administered tiapamil and placebo were compared in 6 male patients (60…
Summary The effect of tiapamil was studied in 9 patients with the Wolff-Parkinson-White syndrome using programmed stimulation of…