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Thymine
Known as:
2,4-dihydroxy-5-methylpyrimidine
, 5-methyluracil
, 2,4(1H,3H)-Pyrimidinedione, 5-methyl-
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A chemical compound that is used to make one of the building blocks of DNA. It is a type of pyrimidine.
National Institutes of Health
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Related topics
Related topics
50 relations
Narrower (38)
1,3-dimethylthymine epoxide
1-(2-carboxyethyl)thymine
1-cyclohexylthymine
1-methylthymine
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In Blood
Thymine:SCnc:Pt:CSF:Qn
agonists
analogs & derivatives
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Broader (3)
Pyrimidines
nucleobase
oxypyrimidine
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
M. Tahiliani
,
Kian Peng Koh
,
+8 authors
A. Rao
Science
2009
Corpus ID: 6862390
Methylation Mediation Methylation of cytosine bases, 5-methylcytosine (5mC), in DNA plays an important regulatory role in…
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Highly Cited
2006
Highly Cited
2006
MercuryII-mediated formation of thymine-HgII-thymine base pairs in DNA duplexes.
Y. Miyake
,
H. Togashi
,
+9 authors
A. Ono
Journal of the American Chemical Society
2006
Corpus ID: 45050892
The very specific binding of the HgII ion unexpectedly and significantly stabilizes naturally occurring thymine-thymine base…
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Highly Cited
1999
Highly Cited
1999
Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta.
R. E. Johnson
,
S. Prakash
,
L. Prakash
Science
1999
Corpus ID: 38534427
The RAD30 gene of the yeast Saccharomyces cerevisiae is required for the error-free postreplicational repair of DNA that has been…
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Highly Cited
1999
Highly Cited
1999
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
B. Hendrich
,
U. Hardeland
,
H. Ng
,
J. Jiricny
,
A. Bird
Nature
1999
Corpus ID: 4413207
In addition to its well-documented effects on gene silencing, cytosine methylation is a prominent cause of mutations. In humans…
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Highly Cited
1996
Highly Cited
1996
Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase ζ
J. Nelson
,
C. Lawrence
,
D. Hinkle
Science
1996
Corpus ID: 5874978
The REV3 and REV7 genes of the yeast Saccharomyces cerevisiae are required for DNA damage-induced mutagenesis. The Rev3 and Rev7…
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Highly Cited
1991
Highly Cited
1991
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide.
P. Nielsen
,
M. Egholm
,
R. Berg
,
O. Buchardt
Science
1991
Corpus ID: 45590767
A polyamide nucleic acid (PNA) was designed by detaching the deoxyribose phosphate backbone of DNA in a computer model and…
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Highly Cited
1989
Highly Cited
1989
Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
T. Kocher
,
W. Thomas
,
+4 authors
A. Wilson
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 13226887
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify…
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Highly Cited
1986
Highly Cited
1986
DNA bending at adenine · thymine tracts
H. Koo
,
Hen-Ming Wu
,
D. Crothers
Nature
1986
Corpus ID: 4370805
Intrinsic bending of DNA molecules results from local structural polymorphism in regions of homopolymeric dA · dT which are at…
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Highly Cited
1977
Highly Cited
1977
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.
F. Bolivar
,
R. Rodriguez
,
+5 authors
S. Falkow
Gene
1977
Corpus ID: 25355415
Highly Cited
1977
Highly Cited
1977
A new method for sequencing DNA.
A. Maxam
,
W. Gilbert
Proceedings of the National Academy of Sciences…
1977
Corpus ID: 41429409
DNA can be sequenced by a chemical procedure that breaks a terminally labeled DNA molecule partially at each repetition of a base…
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