Thymine

Known as: 2,4-dihydroxy-5-methylpyrimidine, 5-methyluracil, 2,4(1H,3H)-Pyrimidinedione, 5-methyl- 
A chemical compound that is used to make one of the building blocks of DNA. It is a type of pyrimidine.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The prevalent DNA modification in higher organisms is the methylation of cytosine to 5-methylcytosine (5mC), which is partially… (More)
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Highly Cited
2009
Highly Cited
2009
DNA cytosine methylation is crucial for retrotransposon silencing and mammalian development. In a computational search for… (More)
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Highly Cited
2008
Highly Cited
2008
Evidence for active DNA demethylation in vertebrates is accumulating, but the mechanisms and enzymes remain unclear. Using… (More)
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Highly Cited
2004
Highly Cited
2004
Human DNA polymerase η (Pol η) modulates susceptibility to skin cancer by promoting DNA synthesis past sunlight-induced… (More)
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Highly Cited
1999
Highly Cited
1999
In addition to its well-documented effects on gene silencing, cytosine methylation is a prominent cause of mutations. In humans… (More)
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Highly Cited
1996
Highly Cited
1996
The REV3 and REV7 genes of the yeast Saccharomyces cerevisiae are required for DNA damage-induced mutagenesis. The Rev3 and Rev7… (More)
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Highly Cited
1991
Highly Cited
1991
A polyamide nucleic acid (PNA) was designed by detaching the deoxyribose phosphate backbone of DNA in a computer model and… (More)
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Highly Cited
1989
Highly Cited
1989
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify… (More)
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Highly Cited
1987
Highly Cited
1987
Several single-base substitution mutations have been introduced into the lacZa gene in cloning vector M13mp2, at 40-60… (More)
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Highly Cited
1986
Highly Cited
1986
Intrinsic bending of DNA molecules results from local structural polymorphism in regions of homopolymeric dA · dT which are at… (More)
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