Thymine

Known as: 2,4-dihydroxy-5-methylpyrimidine, 5-methyluracil, 2,4(1H,3H)-Pyrimidinedione, 5-methyl- 
A chemical compound that is used to make one of the building blocks of DNA. It is a type of pyrimidine.
National Institutes of Health

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Narrower (37)

1,3-dimethylthymine epoxide1-cyclohexylthymine1-methylthymine1-methylthymine osmium tetraoxide bispyridine ester
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In BloodThymine:SCnc:Pt:CSF:QnThymine:SCnc:Pt:Ser/Plas:Qnagonists
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Broader (3)

Pyrimidinesnucleobaseoxypyrimidine

Papers overview

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Highly Cited
2011
Highly Cited
2011
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA.
The prevalent DNA modification in higher organisms is the methylation of cytosine to 5-methylcytosine (5mC), which is partially… (More)
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Highly Cited
2009
Highly Cited
2009
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.
DNA cytosine methylation is crucial for retrotransposon silencing and mammalian development. In a computational search for… (More)
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Highly Cited
2008
Highly Cited
2008
DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45
Evidence for active DNA demethylation in vertebrates is accumulating, but the mechanisms and enzymes remain unclear. Using… (More)
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Highly Cited
2004
Highly Cited
2004
Preferential cis–syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity
Human DNA polymerase η (Pol η) modulates susceptibility to skin cancer by promoting DNA synthesis past sunlight-induced… (More)
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Highly Cited
1999
Highly Cited
1999
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
In addition to its well-documented effects on gene silencing, cytosine methylation is a prominent cause of mutations. In humans… (More)
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Highly Cited
1996
Highly Cited
1996
Thymine-thymine dimer bypass by yeast DNA polymerase zeta.
The REV3 and REV7 genes of the yeast Saccharomyces cerevisiae are required for DNA damage-induced mutagenesis. The Rev3 and Rev7… (More)
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Highly Cited
1991
Highly Cited
1991
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide.
A polyamide nucleic acid (PNA) was designed by detaching the deoxyribose phosphate backbone of DNA in a computer model and… (More)
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Highly Cited
1989
Highly Cited
1989
Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
With a standard set of primers directed toward conserved regions, we have used the polymerase chain reaction to amplify… (More)
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Highly Cited
1987
Highly Cited
1987
Rapid and efficient site-specific mutagenesis without phenotypic selection.
Several single-base substitution mutations have been introduced into the lacZa gene in cloning vector M13mp2, at 40-60… (More)
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Highly Cited
1986
Highly Cited
1986
DNA bending at adenine · thymine tracts
Intrinsic bending of DNA molecules results from local structural polymorphism in regions of homopolymeric dA · dT which are at… (More)
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