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Thiothixene

Known as: Thiothixine, Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)- 
A thioxanthene derivative and a dopamine antagonist with antipsychotic property. Thiothixene blocks postsynaptic dopamine receptors in the mesolimbic… 
National Institutes of Health

Related topics

Related topics

23 relations
Adrenergic alpha-Antagonists [MoA]Blood Coagulation DisordersComatoseDrug Allergy

Broader (6)

Antipsychotic AgentsDopamine AntagonistsPhenazinesTranquilizing Agents

Narrower (3)

NavaneP-4657 BThiothixene hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Schizophrenia patients at higher risk of diabetes, hypertension and hyperlipidemia: A population-based study
Review
2010
Review
2010
Pharmacological interventions for borderline personality disorder.
BACKGROUND Drugs are widely used in borderline personality disorder (BPD) treatment, chosen because of properties known from… 
Review
2005
Review
2005
Schizophrenia and comorbid human immunodeficiency virus or hepatitis C virus.
Patients with schizophrenia are at significantly increased risk for infection with human immunodeficiency virus (HIV), hepatitis… 
Highly Cited
2004
Highly Cited
2004
Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse…
Highly Cited
1997
Highly Cited
1997
The effect of antipsychotic medication on relative cerebral blood perfusion in schizophrenia: Assessment with technetium-99m hexamethyl-propyleneamine oxime single photon emission computed tomography
Highly Cited
1997
Highly Cited
1997
Muscarinic m4 receptor activation by some atypical antipsychotic drugs.
Highly Cited
1993
Highly Cited
1993
Neuroleptic medications inhibit complex I of the electron transport chain
Neuroleptic medications are prescribed to millions of patients, but their use is limited by potentially irreversible… 
Highly Cited
1984
Highly Cited
1984
Clinical comparison of thiothixene and thioridazine in schizophrenic adolescents.
Of 21 schizophrenic adolescents given thiothixene or thioridazine, many responded poorly or experienced sedation. Because… 
Highly Cited
1981
Highly Cited
1981
Correlation between antiavoidance activities of antipsychotic drugs in rats and daily clinical doses
Highly Cited
1974
Highly Cited
1974
Thiothixene-induced hyponatremia.
Since the initial description by Schwartz et al1of a syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a… 
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