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Thioredoxin 1

Known as: Thioredoxin-1 
National Institutes of Health

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Thioredoxins

Papers overview

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Highly Cited
2012
Highly Cited
2012
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway.
DJ-1, which is linked to recessively inherited Parkinson's disease when mutated, is a multi-functional protein with anti-oxidant… 
Highly Cited
2012
Highly Cited
2012
Thioredoxin-1 Promotes Anti-Inflammatory Macrophages of the M2 Phenotype and Antagonizes Atherosclerosis
Objective—Oxidative stress is believed to play a key role in cardiovascular disorders. Thioredoxin (Trx) is an oxidative stress… 
Highly Cited
2011
Highly Cited
2011
Increased thioredoxin-1 production in human naturally occurring regulatory T cells confers enhanced tolerance to oxidative stress.
Levels of regulatory T cells (Tregs) are increased in different cancer types as well as in inflammatory diseases, such as… 
Highly Cited
2010
Highly Cited
2010
HIF-1 alpha signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells.
Highly Cited
2009
Highly Cited
2009
The Physiology and Pathophysiology of the Hyperbaric and Diving Environments Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo
Tatyana N. Milovanova, Veena M. Bhopale, Elena M. Sorokina, Jonni S. Moore, Thomas K. Hunt, Martin Hauer-Jensen, Omaida C… 
Review
2008
Review
2008
Redox compartmentalization in eukaryotic cells.
Highly Cited
2005
Highly Cited
2005
&agr;-Adrenergic Receptor–Stimulated Hypertrophy in Adult Rat Ventricular Myocytes Is Mediated via Thioredoxin-1–Sensitive Oxidative Modification of Thiols on Ras
Background—&agr;-Adrenergic receptor (&agr;AR)–stimulated hypertrophy in adult rat ventricular myocytes is mediated by reactive… 
Highly Cited
2003
Highly Cited
2003
Thioredoxin redox signaling in the ischemic heart: an insight with transgenic mice overexpressing Trx1.
Highly Cited
2003
Highly Cited
2003
Thioredoxin as a Molecular Target of Cyclopentenone Prostaglandins*
Prostaglandin (PG) D2, a major cyclooxygenase product in a variety of tissues and cells, readily undergoes dehydration to yield… 
Highly Cited
2002
Highly Cited
2002
Overexpression of Thioredoxin-1 in Transgenic Mice Attenuates Adriamycin-Induced Cardiotoxicity
Background—Adriamycin (ADR) is an anticancer drug known to cause severe cardiac toxicity by generating free radicals. We… 
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