Thioredoxin 1

Known as: Thioredoxin-1 
 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
DJ-1, which is linked to recessively inherited Parkinson's disease when mutated, is a multi-functional protein with anti-oxidant… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Silent information regulator 1 (Sirt1), a class III histone deacetylase, retards aging and protects the heart from… (More)
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Highly Cited
2008
Highly Cited
2008
Nitric oxide acts substantially in cellular signal transduction through stimulus-coupled S-nitrosylation of cysteine residues… (More)
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Highly Cited
2006
Highly Cited
2006
Metal toxicity often includes the generation of reactive oxygen species (ROS) and subsequent oxidative stress, but whether metals… (More)
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Highly Cited
2003
Highly Cited
2003
Thioredoxin 1 (Trx1) has redox-sensitive cysteine residues and acts as an antioxidant in cells. However, the extent of Trx1… (More)
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Highly Cited
2002
Highly Cited
2002
Thioredoxin 1 (Trx) is a known redox regulator that is implicated in the redox control of cell growth and apoptosis inhibition… (More)
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Highly Cited
2002
Highly Cited
2002
Hypoxia-inducible factor 1 (HIF-1), a heterodimer of HIF-1alpha and HIF-1beta subunits, is a transcriptional activator central to… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Adriamycin (ADR) is an anticancer drug known to cause severe cardiac toxicity by generating free radicals. We… (More)
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Review
2001
Review
2001
The mammalian thioredoxins are a family of small (approximately 12 kDa) redox proteins that undergo NADPH-dependent reduction by… (More)
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Review
2000
Review
2000
The thioredoxins are ubiquitous proteins containing a conserved -Trp-Cys-Gly-Pro-Cys-Lys- redox catalytic site. Mammalian… (More)
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