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Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha.
Endothelial progenitor cells (EPCs) are essential in vasculogenesis and wound healing, but their circulating and wound level numbers are decreased in diabetes. This study aimed to determineExpand
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Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning.
Carbon monoxide (CO) poisoning is common in modern society, resulting in significant morbidity and mortality in the United States annually. Over the past two decades, sufficient information has beenExpand
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Delayed neuropathology after carbon monoxide poisoning is immune-mediated.
The neuropathological sequelae of carbon monoxide (CO) poisoning cannot be explained by hypoxic stress alone. CO poisoning also causes adduct formation between myelin basic protein (MBP) andExpand
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Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota.
BACKGROUND & AIMS The gut microbiota is a complex and densely populated community in a dynamic environment determined by host physiology. We investigated how intestinal oxygen levels affect theExpand
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Carbon monoxide poisoning--a public health perspective.
Carbon monoxide (CO) may be the cause of more than one-half of the fatal poisonings reported in many countries; fatal cases also are grossly under-reported or misdiagnosed by medical professionals.Expand
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Delayed neuropsychologic sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen.
STUDY OBJECTIVE Carbon monoxide (CO) poisoning is a major clinical problem. The risk of morbidity and the most effective treatment have not been clearly established. We measured the incidence ofExpand
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Hyperbaric Oxygen: Its Mechanisms and Efficacy
  • S. Thom
  • Medicine
  • Plastic and reconstructive surgery
  • 1 January 2011
Background: This article outlines therapeutic mechanisms of hyperbaric oxygen therapy and reviews data on its efficacy for clinical problems seen by plastic and reconstructive surgeons. Methods: TheExpand
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Oxidative stress is fundamental to hyperbaric oxygen therapy.
  • S. Thom
  • Biology, Medicine
  • Journal of applied physiology
  • 1 March 2009
The goal of this review is to outline advances addressing the role that reactive species of oxygen and nitrogen play in therapeutic mechanisms of hyperbaric oxygen. The review will be organizedExpand
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Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury
BackgroundLocal and systemic inflammatory responses are initiated early after traumatic brain injury (TBI), and may play a key role in the secondary injury processes resulting in neuronal loss andExpand
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