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Thiazolidinediones

Known as: glitazone, thiazolidinedione, Glitazones 
THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-modulated transcription factor that governs the… Expand
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Review
2018
Review
2018
Peroxisome proliferator-activated receptors (PPARs) are a well-known pharmacological target for the treatment of multiple… Expand
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Review
2018
Review
2018
Peroxisome proliferator-activated receptor γ (PPARγ), a ligand-dependent transcription factor highly expressed in adipocytes, is… Expand
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Review
2017
Review
2017
ABSTRACT Introduction: Alzheimer’s disease (AD) is the most common cause of dementia in the elderly. Pharmacological treatment of… Expand
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Review
2011
Review
2011
BACKGROUND Latent autoimmune diabetes in adults (LADA) is a slowly developing type 1 diabetes. OBJECTIVES To compare… Expand
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Review
2006
Review
2006
Nonalcoholic steatohepatitis (NASH), the lynchpin between steatosis and cirrhosis in the spectrum of nonalcoholic fatty liver… Expand
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Highly Cited
2004
Highly Cited
2004
Adiponectin is an adipocyte-specific secretory protein that circulates in serum as a hexamer of relatively low molecular weight… Expand
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Highly Cited
2002
Highly Cited
2002
The insulin-sensitizing effects of thiazolidinediones are thought to be mediated through peroxisome proliferator-activated… Expand
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Review
1996
Review
1996
Insulin resistance, characterized by reduced responsiveness to normal circulating concentrations of insulin, is a common feature… Expand
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Highly Cited
1995
Highly Cited
1995
Thiazolidinedione derivatives are antidiabetic agents that increase the insulin sensitivity of target tissues in animal models of… Expand
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