Tetracycline

Known as: 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide, Tsiklomitsin, (4S,4AS,5as,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide 
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
010020030019462016

Papers overview

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Highly Cited
2001
Highly Cited
2001
Tetracyclines were discovered in the 1940s and exhibited activity against a wide range of microorganisms including gram-positive… (More)
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Highly Cited
2001
Highly Cited
2001
In this study, we used PCR typing methods to assess the presence of tetracycline resistance determinants conferring ribosomal… (More)
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Highly Cited
2001
Highly Cited
2001
Specific primer pairs were selected for the PCR amplification of 14 tetracycline resistant genes commonly found in Gram positive… (More)
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Highly Cited
2001
Highly Cited
2001
Phylogenetic analysis of tetracycline resistance genes encoding the ribosomal protection proteins (RPPs) revealed the… (More)
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Highly Cited
2000
Highly Cited
2000
Regulatory elements that control tetracycline resistance in Escherichia coli were previously converted into highly specific… (More)
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Highly Cited
2000
Highly Cited
2000
We have used the recently determined atomic structure of the 30S ribosomal subunit to determine the structures of its complexes… (More)
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Highly Cited
2000
Highly Cited
2000
The tetracycline repressor (TetR) regulates the most abundant resistance mechanism against the antibiotic tetracycline in gram… (More)
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Highly Cited
1999
Highly Cited
1999
Intracellular bacteria have been described in several species of filarial nematodes, but their relationships with, and effects on… (More)
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Highly Cited
1998
Highly Cited
1998
Ischemic stroke is the most common life-threatening neurological disease and has limited therapeutic options. One component of… (More)
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Highly Cited
1980
Highly Cited
1980
Tetracycline resistance encoded by four genetically different determinants residing on plasmids in Escherichia coli was shown to… (More)
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