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Tetracycline

Known as: 4-(Dimethylamino)-1,4,4A,5,5A,6,11,12A-Octahydro-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-2-Naphthacenecarboxamide, Tsiklomitsin, (4S,4AS,5as,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide 
A broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The lipopolysaccharide (LPS) of Gram negative bacteria is a well-known inducer of the innate immune response. Toll-like receptor… Expand
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Highly Cited
2007
Highly Cited
2007
Helicobacter pylori (H. pylori) remains a prevalent, worldwide, chronic infection. Though the prevalence of this infection… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly recognized in infections among persons in the… Expand
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Review
2002
Review
2002
Significant progress and new insights have been gained in the 4 years since the first Maastricht Consensus Report, necessitating… Expand
Highly Cited
2000
Highly Cited
2000
We have used the recently determined atomic structure of the 30S ribosomal subunit to determine the structures of its complexes… Expand
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Highly Cited
1997
Highly Cited
1997
A set of Saccharomyces cerevisiae expression vectors has been developed in which transcription is driven by a hybrid tetO‐CYC1… Expand
Highly Cited
1992
Highly Cited
1992
  • M. Gossen, H. Bujard
  • Proceedings of the National Academy of Sciences…
  • 1992
  • Corpus ID: 37196165
Control elements of the tetracycline-resistance operon encoded in Tn10 of Escherichia coli have been utilized to establish a… Expand
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Highly Cited
1991
Highly Cited
1991
NHIK 3025 cells were incubated with Photofrin II (PII) and/or tetra (3‐hydroxyphenyl)porphyrin (3THPP) and exposed to light at… Expand
Highly Cited
1980
Highly Cited
1980
Abstract Plasmid cloning vectors that enable insertion of DNA fragments between the inducible ara (arabinose) promoter and the… Expand
Highly Cited
1977
Highly Cited
1977
In vitro recombination techniques were used to construct a new cloning vehicle, pBR322. This plasmid, derived from pBR313, is a… Expand