Tenofovir

Known as: Anhydrous tenofovir, (R)-9-(2-phosphonomethoxypropyl)adenine, Tenofovir (anh.) 
An adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
An estimated 170 million persons worldwide have hepatitis C virus (HCV) infection (1), including 2.7 million to 3.9 million in… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVE Despite widespread HAART use, HIV disease remains associated with increased risk of kidney disease. Whether tenofovir… (More)
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Highly Cited
2011
Highly Cited
2011
Tenofovir is an acyclic nucleotide analogue reverse-transcriptase inhibitor structurally similar to the nephrotoxic drugs… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Efavirenz with tenofovir-disoproxil-fumarate and emtricitabine is a preferred antiretroviral regimen for treatment… (More)
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Highly Cited
2010
Highly Cited
2010
Tenofovir, a widely prescribed antiretroviral medication for treatment of HIV-1 infection, is infrequently associated with renal… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Atazanavir/ritonavir is as effective as lopinavir/ritonavir, with a more favourable lipid profile and less… (More)
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Highly Cited
2007
Highly Cited
2007
Acyclic nucleotide phosphonates (adefovir, cidofovir, and tenofovir) are eliminated predominantly into the urine, and renal… (More)
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Highly Cited
2003
Highly Cited
2003
We report 3 cases of renal toxicity associated with use of the antiviral agent tenofovir. Renal failure, proximal tubular… (More)
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Highly Cited
2002
Highly Cited
2002
Drug-associated dysfunction of mitochondria is believed to play a role in the etiology of the various adverse symptoms that occur… (More)
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Highly Cited
2002
Highly Cited
2002
Although nephrotoxicity of cidofovir and adefovir is well established, no renal side effects have been observed yet with… (More)
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