Tenofovir disoproxil fumarate

Known as: PMPA Prodrug, TDF, Fumarate, Tenofovir Disoproxil 
A pro-drug, fumaric acid salt form of tenofovir, a nucleoside reverse transcriptase inhibitor analog of adenosine. Tenofovir disoproxil fumarate is… (More)
National Institutes of Health

Related topics

Related topics

17 relations
Acquired Immunodeficiency SyndromeDrug AllergyHIV InfectionsHepatitis B
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Narrower (5)

AtriplaCompleraStribildTruvada
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Broader (2)

Tenofovirtenofovir disoproxil

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Randomized comparison of tenofovir disoproxil fumarate vs emtricitabine and tenofovir disoproxil fumarate in patients with lamivudine-resistant chronic hepatitis B.
BACKGROUND & AIMS Tenofovir disoproxil fumarate (TDF) is active against lamivudine-resistant hepatitis B virus (HBV) infection… (More)
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Highly Cited
2013
Highly Cited
2013
Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study
BACKGROUND Whether long-term suppression of replication of hepatitis B virus (HBV) has any beneficial effect on regression of… (More)
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Highly Cited
2013
Highly Cited
2013
Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir Study): a randomised, double-blind, placebo-controlled phase 3 trial
BACKGROUND Antiretroviral pre-exposure prophylaxis reduces sexual transmission of HIV. We assessed whether daily oral use of… (More)
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Highly Cited
2011
Highly Cited
2011
Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease.
UNLABELLED Data are limited on the safety and effectiveness of oral antivirals other than lamivudine and adefovir dipivoxil for… (More)
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Highly Cited
2008
Highly Cited
2008
Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.
BACKGROUND Tenofovir disoproxil fumarate (DF) is a nucleotide analogue and a potent inhibitor of human immunodeficiency virus… (More)
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Highly Cited
2007
Highly Cited
2007
The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years.
OBJECTIVE To characterize the safety profile of tenofovir disoproxil fumarate (DF) for the treatment of HIV infection in adults… (More)
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Highly Cited
2005
Highly Cited
2005
Changes in renal function associated with tenofovir disoproxil fumarate treatment, compared with nucleoside reverse-transcriptase inhibitor treatment.
In our large observational cohort, use of tenofovir disoproxil fumarate (n=344) was associated with a greater decline in renal… (More)
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Review
2004
Review
2004
Tenofovir disoproxil fumarate: clinical pharmacology and pharmacokinetics.
Tenofovir disoproxil fumarate (tenofovir DF) is an oral prodrug of tenofovir, a nucleotide (nucleoside monophosphate) analogue… (More)
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Highly Cited
2004
Highly Cited
2004
Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial.
CONTEXT Tenofovir disoproxil fumarate (DF) is a once-daily nucleotide analogue reverse transcriptase inhibitor. OBJECTIVE To… (More)
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Highly Cited
2003
Highly Cited
2003
Tenofovir disoproxil fumarate.
Tenofovir disoproxil fumarate (tenofovir DF) is a bioavailable prodrug of tenofovir, a potent nucleotide analogue reverse… (More)
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