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Teniposide

Known as: Thenylidene Lignan, Teniposid, PTG 
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with… 
National Institutes of Health

Related topics

Related topics

35 relations

Broader (4)

Antineoplastic AgentsAntineoplastic Agents, Phytogenicpodofiloxpodophyllin
CHVmP-VB protocolCYP2C19 protein, humanCarcinoma, Small CellCisplatin/Doxorubicin/Melphalan/Teniposide regimen

Narrower (11)

LTPP protocolMBVP protocolNSC-122819OPEC-D protocol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Acute promyelocytic leukemia with, t( 15; 17) abnormality after, chemotherapy containing etoposide for, Langerhans cell histiocytosis
of their disease. Obviously, a randomized double-blind study is a much better design to assess drug efficacy. However, we… 
Highly Cited
2006
Highly Cited
2006
Genetic thrombophilic mutations among couples with recurrent miscarriage.
BACKGROUND Some cases of recurrent first trimester miscarriage (RM)-the loss of three or more consecutive pregnancies at <12… 
Highly Cited
2003
Highly Cited
2003
Investigation of the putative immunodominant T cell epitopes in coeliac disease
Background: Coeliac disease (CD) is an enteropathy mediated by gluten specific T cells which secrete interferon γ (IFN-γ) when… 
2003
2003
Protein Targeting to Glycogen Overexpression Results in the Specific Enhancement of Glycogen Storage in 3T3-L1 Adipocytes*
Protein phosphatase-1 (PP1) plays an important role in the regulation of glycogen synthesis by insulin. Protein targeting to… 
Highly Cited
2002
Highly Cited
2002
Antimicrobial Peptides Initiate IL-1β Posttranslational Processing: A Novel Role Beyond Innate Immunity
Human monocytes stimulated with LPS produce large quantities of prointerleukin-1β, but little of this cytokine product is… 
Highly Cited
1992
Highly Cited
1992
Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation
Abstract. We have previously observed that the DNA topoisomerase I inhibitor camptothecin (CAM), or DNA topoisomerase II… 
Review
1992
Review
1992
Radiotherapy- and chemotherapy-induced myelodysplasia and acute myeloid leukemia. A review.
Highly Cited
1990
Highly Cited
1990
Reduction of drug accumulation and DNA topoisomerase II activity in acquired teniposide-resistant human cancer KB cell lines.
We have isolated stable teniposide (VM26)-resistant cell lines from human cancer KB cells by stepwise exposure to increasing… 
Highly Cited
1986
Highly Cited
1986
Chloroquine enhancement of anticancer drug cytotoxicity in multiple drug resistant human leukemic cells.
Highly Cited
1970
Highly Cited
1970
4'-Demethyl-epipodophyllotoxin thenylidene glucoside (VM 26), a podophyllum compound with a new mechanism of action.
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