Teniposide

Known as: Thenylidene Lignan, Teniposid, PTG 
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The objective of the present study was to develop a rat model that replicates the natural history and metabolic characteristics… (More)
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Highly Cited
2001
Highly Cited
2001
Virulence in Toxoplasma gondii is strongly influenced by the genotype of the parasite. Type I strains uniformly cause rapid death… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptosis induced by DNA damage and other stresses can proceed via expression of Fas ligand (FasL) and ligation of its receptor… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND Phyto-oestrogens are a group of naturally occurring chemicals derived from plants; they have a structure similar to… (More)
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Highly Cited
1996
Highly Cited
1996
Dietary phosphorus (P) restriction is known to ameliorate secondary hyperparathyroidism in renal failure patients. In early renal… (More)
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Highly Cited
1994
Highly Cited
1994
PURPOSE The development of leukemia is one of the most serious long-term complications of modern treatment for Hodgkin's disease… (More)
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Highly Cited
1993
Highly Cited
1993
DNA strand breaks which occur in HL-60 cells as a result of activation of endonuclease during apoptosis induced by cell treatment… (More)
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Review
1987
Review
1987
Etoposide and teniposide are semisynthetic derivatives of podophyllotoxin and are increasingly used in cancer medicine… (More)
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Highly Cited
1987
Highly Cited
1987
Resistance to the cytotoxic effects of many natural product drugs after exposure to a single agent is a common observation. The… (More)
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Highly Cited
1985
Highly Cited
1985
The anticancer agents 4'-demethylepipodophyllotoxin-4-(4,6-O-ethylidene-beta-D-glucopyra noside (etoposide) (VP16-213) and 4… (More)
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