Tacrolimus Binding Protein 1A

Known as: Macrophilin-12, FK506-Binding Protein 1, FKBP 12 
A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Duchenne muscular dystrophy is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency… (More)
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Highly Cited
2001
Highly Cited
2001
Syncytia arising from the fusion of cells expressing a lymphotropic human immunodeficiency virus (HIV)-1-encoded envelope… (More)
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Highly Cited
2001
Highly Cited
2001
Candida albicans and Cryptococcus neoformans cause both superficial and disseminated infections in humans. Current antifungal… (More)
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2000
2000
OBJECTIVE Little information is available as to the Ca(2+) release function of the sarcoplasmic reticulum (SR) in heart failure… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In the pathogenesis of cardiac dysfunction in heart failure, a decrease in the activity of the sarcoplasmic reticulum… (More)
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Highly Cited
1998
Highly Cited
1998
FKBP12, a cis–trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, is ubiquitouslyexpressed and… (More)
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1997
1997
FKBP12 was removed from ryanodine receptors (RyRs) by incubation of rabbit skeletal muscle terminal cisternae membranes with… (More)
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Highly Cited
1996
Highly Cited
1996
Rapamycin, a potent immunosuppressive agent, binds two proteins: the FK506-binding protein (FKBP12) and the FKBP-rapamycin… (More)
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Highly Cited
1996
Highly Cited
1996
The calcium release channels (CRC)/ryanodine receptors of skeletal (Sk) and cardiac (C) muscle sarcoplasmic reticulum (SR) are… (More)
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Highly Cited
1995
Highly Cited
1995
The immunosuppressant drug FK506 binds to the immunophilin protein FKBP12 and inhibits its prolyl isomerase activity… (More)
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