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Tacrolimus Binding Protein 1A
Known as:
Macrophilin-12
, FK506-Binding Protein 1
, FKBP 12
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A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl…
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National Institutes of Health
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Related topics
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9 relations
FKBP1A protein, human
FKBP1A wt Allele
In Blood
Process of secretion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Bcl-2 and FKBP12 bind to IP3 and ryanodine receptors at overlapping sites: the complexity of protein-protein interactions for channel regulation.
T. Vervliet
,
J. Parys
,
G. Bultynck
Biochemical Society Transactions
2015
Corpus ID: 41067098
The 12- and 12.6-kDa FK506-binding proteins, FKBP12 (12-kDa FK506-binding protein) and FKBP12.6 (12.6-kDa FK506-binding protein…
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Highly Cited
2006
Highly Cited
2006
Structural characterization of the RyR1-FKBP12 interaction.
M. Samsó
,
Xiaohua Shen
,
P. Allen
Journal of Molecular Biology
2006
Corpus ID: 30580122
Highly Cited
2001
Highly Cited
2001
FKBP12 Binding Modulates Ryanodine Receptor Channel Gating*
M. Gaburjáková
,
J. Gaburjáková
,
+4 authors
A. Marks
Journal of Biological Chemistry
2001
Corpus ID: 43814996
The ryanodine receptor (RyR1)/calcium release channel on the sarcoplasmic reticulum of skeletal muscle is comprised of four 565…
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1999
1999
High Throughput Scintillation Proximity Assay for the Identification of FKBP-12 Ligands
F. Graziani
,
L. Aldegheri
,
G. Terstappen
Journal of biomolecular screening
1999
Corpus ID: 25124864
A high throughput scintillation proximity assay (SPA) was developed to identify novel ligands of FKBP-12, an immunophilin with…
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Highly Cited
1998
Highly Cited
1998
Oral administration of a nonimmunosuppressant FKBP‐12 ligand speeds nerve regeneration
B. Gold
,
M. Zeleny-Pooley
,
P. Chaturvedi
,
Min‐Sheng Wang
NeuroReport
1998
Corpus ID: 9615237
WE recently showed that s.c. injections of a nonimmunosuppressant FK506 binding protein-12 (FKBP-12) ligand (V-10,367…
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1998
1998
FKBP12 Modulates Gating of the Ryanodine Receptor/Calcium Release Channel a
K. Ondrias
,
S. Marx
,
M. Gaburjáková
,
A. Marks
Annals of the New York Academy of Sciences
1998
Corpus ID: 30566131
ABSTRACT: Excitation‐contraction (EC) coupling in muscle requires the activation of intracellular calcium release channels (CRC…
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1997
1997
FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiae
Clara M. Alarcon
,
Joseph Heitman
Molecular and Cellular Biology
1997
Corpus ID: 33401947
The peptidyl-prolyl isomerase FKBP12 was originally identified as the intracellular receptor for the immunosuppressive drugs…
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1995
1995
Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface.
J. Luengo
,
D. Yamashita
,
+7 authors
T. Newman-Tarr
Chemistry and Biology
1995
Corpus ID: 25750732
1993
1993
The mammalian heat shock protein binding immunophilin (p59/HBI) is an ATP and GTP binding protein.
S. Le Bihan
,
J. Renoir
,
+4 authors
E. Baulieu
Biochemical and Biophysical Research…
1993
Corpus ID: 46049689
A protein of M(r) 59,000 (p59) was recently cloned and identified as a Heat shock protein Binding Immunophilin (p59/HBI). It…
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1992
1992
Solution structure of FK506 bound to FKBP‐12
C. Lepre
,
J. Thomson
,
Jonathan M. Moore
FEBS Letters
1992
Corpus ID: 41469360
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