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TYRP1 protein, human

Known as: melanoma antigen gp75, human, brown locus protein, human, TYRP 
5,6-dihydroxyindole-2-carboxylic acid oxidase (537 aa, ~61 kDa) is encoded by the human TYRP1 gene. This protein plays a role in melanin biosynthesis… 
National Institutes of Health

Related topics

Related topics

13 relations
Enzyme GeneGlycoproteinsMelanogenesisMelanogenesis Pathway

Broader (3)

Membrane GlycoproteinsOxidoreductaseTyrosinase related protein-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
The acclimative response of the main light-harvesting chlorophyll a/b-protein complex of photosystem II (LHCII) to elevated irradiances at the level of trimeric subunits.
2003
2003
Synthesis of optically active tetrameric melanin intermediates by oxidation of the melanogenic precursor 5,6-dihydroxyindole-2-carboxylic acid under biomimetic conditions
2000
2000
Cloning and Random Mutagenesis of the Erwinia herbicola tyrR Gene for High-Level Expression of Tyrosine Phenol-Lyase
ABSTRACT Tyrosine phenol-lyase (Tpl), which can synthesize 3,4-dihydroxyphenylalanine from pyruvate, ammonia, and catechol, is a… 
1998
1998
Adenovirus-mediated expression of melanoma antigen gp75 as immunotherapy for metastatic melanoma
Melanocyte differentiation antigens, such as the brown locus protein gp75, are potential biological targets for immunotherapy. We… 
Highly Cited
1996
Highly Cited
1996
Functional Analysis of a p21WAF1,CIP1,SDI1 Mutant (Arg94 → Trp) Identified in a Human Breast Carcinoma
Human p21 (also known as WAF1, CIP1, or SDI1) is a dual inhibitor of cyclin dependent kinases (CDKs) and the replication factor… 
Highly Cited
1993
Highly Cited
1993
The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts.
Many genes mapping to pigmentation loci are involved in the regulation of melanin synthesis in the mouse. The brown (b) locus… 
1992
1992
Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to platelets.
Type IIB von Willebrand disease is an autosomal dominant bleeding disorder characterized by the selective loss of high molecular… 
1991
1991
Phosphotyrosine as a specificity determinant for casein kinase‐2, a growth related Ser/Thr‐specific protein kinase
1981
1981
Photochrome-mediated regulation of messenger RNAs for the small subunit of ribulose 1, 5-bisphosphate carboxylase and the light-harvesting chlorophyll a/b-protein in Lemna gibba
Brief red illumination (10 min/8 hr) of Lemna gibba L. G-3 growing heterotrophically in the dark increases the growth of the… 
Highly Cited
1981
Highly Cited
1981
White Light Effects on the mRNA for the Light-Harvesting Chlorophyll a/b-Protein in Lemna gibba L. G-3.
Translation products of poly(A) mRNA isolated from Lemna gibba L. G-3 include a major polypeptide of 32,000 daltons which is… 
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