TXNRD1 gene

Known as: Trxr1, TXNRD1, TXNR 
This gene plays a role in the maintenance of cellular redox signaling.
National Institutes of Health

Papers overview

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2013
2013
Intrinsic resistance to agents targeting phosphoinositide 3-kinase (PI3K)/AKT pathway is one of the major challenges in cancer… (More)
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2013
2013
BACKGROUND Endothelial dysfunction precedes pathogenesis of vascular complications in diabetes. In recent years, the mechanisms… (More)
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2012
2012
Ribonucleotide reductase (RNR) activity requires an electron donor, which in bacteria, yeast, and plants is usually either… (More)
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Highly Cited
2010
Highly Cited
2010
The purpose of this work was to study the prognostic influence in breast cancer of thioredoxin reductase 1 (TXNRD1) and… (More)
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Highly Cited
2009
Highly Cited
2009
Selenoproteins contain a highly reactive 21st amino acid selenocysteine (Sec) encoded by recoding of a predefined UGA codon… (More)
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2009
2009
The selenoprotein thioredoxin reductase 1 (TrxR1) is currently recognized as a plausible anticancer drug target. Here we analyzed… (More)
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2008
2008
BACKGROUND Epidemiologic and animal studies provide evidence for a chemopreventive effect of selenium on colorectal cancer, which… (More)
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Highly Cited
2007
Highly Cited
2007
Oxidative stress activates the transcription factor NRF2, which in turn binds cis-acting antioxidant response element (ARE… (More)
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Highly Cited
2005
Highly Cited
2005
Two distinct thioredoxin/thioredoxin reductase systems are present in the cytosol and the mitochondria of mammalian cells… (More)
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1998
1998
Interferons (IFNs) and retinoids are potent biological response modifiers. By using JAK-STAT pathways, IFNs regulate the… (More)
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