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TV-1380

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Therapeutic treatment of cocaine toxicity or addiction is a grand medical challenge. As a promising therapeutic strategy for… Expand
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2018
2018
BACKGROUND TV-1380 is a rationally mutated, human BChE fused to human serum albumin that has high hydrolytic enzymatic activity… Expand
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2016
2016
BACKGROUND TV-1380 (AlbuChE) is a novel recombinant fusion protein of mutated butyrylcholinesterase (BChE) that has increased… Expand
2016
2016
  • S. Curry, S. Coombs
  • Proceedings of the National Academy of Sciences
  • 2016
  • Corpus ID: 205279275
Xiabin Chen et al. (1) describe pioneering work with a modified drug-metabolizing enzyme, a butyrylcholinesterase (BChE) analog… Expand
2016
2016
  • F. Zheng, C. Zhan
  • Proceedings of the National Academy of Sciences
  • 2016
  • Corpus ID: 29919957
As is well known, and also pointed out correctly by Curry and Coombs (1), cocaine has three metabolic pathways associated with… Expand
2016
2016
  • ossi Gilgun-Sherkia, Rom E. Eliazb, +7 authors Shwe Gyawc
  • 2016
  • Corpus ID: 145044520
Background: TV-1380 (AlbuChE) is a novel recombinant fusion protein of mutated butyrylcholinesterase (BChE) that has increased… Expand
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2015
2015
Human plasma butyrylcholinesterase (BChE) contributes to cocaine metabolism and has been considered for use in treating cocaine… Expand