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TV-1380

National Institutes of Health

Related topics

Related topics

4 relations
Albu-BChE

Broader (3)

AlbuminsButyrylcholinesteraseRecombinant Fusion Proteins

Papers overview

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2016
2016
Benzoic acid is not the only important product of accelerated metabolism of cocaine
Xiabin Chen et al. (1) describe pioneering work with a modified drug-metabolizing enzyme, a butyrylcholinesterase (BChE) analog… 
2016
2016
Reply to Curry and Coombs: Benzoic acid is formed predominantly from the benzoyl ester hydrolysis in the presence of cocaine hydrolase
As is well known, and also pointed out correctly by Curry and Coombs (1), cocaine has three metabolic pathways associated with… 
2016
2016
lacebo-controlled evaluation of a bioengineered , ocaine-metabolizing fusion protein , TV-1380 ( AlbuBChE ) , in the reatment of cocaine dependence
Background: TV-1380 (AlbuChE) is a novel recombinant fusion protein of mutated butyrylcholinesterase (BChE) that has increased… 
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