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TUSC4 wt Allele

Known as: NPR2L, NPRL2, Tumor Suppressor Candidate 4 wt Allele 
Human TUSC4 wild-type allele is located in the vicinity of 3p21.3 and is approximately 4 kb in length. This allele, which encodes tumor suppressor… 
National Institutes of Health

Related topics

Related topics

6 relations
3p21.3Cell Proliferation Regulatory ProcessHomo sapiensNeoplastic Cell Transformation

Broader (1)

NPRL2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Sleep-related hypermotor epilepsy (SHE): Contribution of known genes in 103 patients
2018
2018
Loss of a Negative Regulator of mTORC1 Induces Aerobic Glycolysis and Altered Fiber Composition in Skeletal Muscle
Highly Cited
2016
Highly Cited
2016
Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia
The discovery of mutations in DEPDC5 in familial focal epilepsies has introduced a novel pathomechanism to a field so far… 
2015
2015
Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2.
2014
2014
The TORC1 inhibitors Nprl2 and Nprl3 mediate an adaptive response to amino-acid starvation in Drosophila
Target of rapamycin complex 1 (TORC1) is a master regulator of metabolism in eukaryotes that integrates information from multiple… 
2012
2012
NPRL2 is an independent prognostic factor of osteosarcoma.
NPRL2 is a tumor suppressor gene whose inactivation contributes to tumor development. However, NPRL2 expression in osteosarcoma… 
2012
2012
NPRL2 gene expression in the progression of colon tumors.
Genetic and epigenetic factors affecting DNA methylation and gene expression are known to be involved in the development of colon… 
2011
2011
Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines
Epigenetic mechanisms are frequently deregulated in cancer cells and can lead to the silencing of genes with tumor suppressor… 
2010
2010
Npr2, Yeast Homolog of the Human Tumor Suppressor NPRL2, Is a Target of Grr1 Required for Adaptation to Growth on Diverse Nitrogen Sources
ABSTRACT Npr2, a putative “nitrogen permease regulator” and homolog of the human tumor suppressor NPRL2, was found to interact… 
Highly Cited
2009
Highly Cited
2009
A Genome-Wide Screen for Regulators of TORC1 in Response to Amino Acid Starvation Reveals a Conserved Npr2/3 Complex
TORC1 is a central regulator of cell growth in response to amino acid availability, yet little is known about how it is regulated… 
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