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TUBEROUS SCLEROSIS 2 (disorder)

Known as: TSC2, TUBEROUS SCLEROSIS 2 
Tuberous sclerosis mapped to chromosome 16p13.3 (TSC2 gene).
National Institutes of Health

Related topics

Related topics

31 relations
Attention Deficit DisorderAutistic DisorderAutosomal dominant inheritanceCardiac rhabdomyoma

Broader (1)

Tuberous Sclerosis

Papers overview

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2011
2011
An Australian tuberous sclerosis cohort: Are surveillance guidelines being met?
Aim:  This study aims to describe the phenotypic and genotypic characteristics of 45 Australian patients with tuberous sclerosis… 
2009
2009
Renal and liver tumors in Tsc2+/− mice, a model of tuberous sclerosis complex, do not respond to treatment with atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor
Inactivating mutations of the tumor suppressor gene TSC2 are associated with tumorigenesis in tuberous sclerosis complex (TSC… 
2009
2009
Growth Factors , Cytokines , Cell Cycle Molecules The Methylation of the TSC 2 Promoter Underlies the Abnormal Growth of TSC 2 Angiomyolipoma-Derived Smooth Muscle Cells
From the Laboratory of Pharmacology,* the Medical Genetic Unit, the Division of Pathology, the Disabled Advanced Medical… 
2008
2008
Toponomics Analysis of Functional Interactions of the Ubiquitin Ligase PAM (Protein Associated with Myc) during Spinal Nociceptive Processing*S
Protein associated with Myc (PAM) is a giant E3 ubiquitin ligase of 510 kDa. Although the role of PAM during neuronal development… 
2005
2005
Distinct Allelic Variants of TSC1 and TSC2 in Epilepsy-Associated Cortical Malformations Without Balloon Cells
Epilepsy-associated malformations of cortical development (MCDs) comprise a variety of dysplastic and neoplastic lesions of yet… 
Review
2005
Review
2005
Clinical and molecular insights into lymphangioleiomyomatosis.
Lymphangioleiomyomatosis (LAM) is a rare disease of women that is characterized by a proliferation of abnormal smooth muscle-like… 
2001
2001
Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis
Abstract Tuberous sclerosis complex (TSC) is a multisystemic disorder characterized by systemic hamartomas. Although the disease… 
1998
1998
Biallelic mutations of the Tsc2 gene in chemically induced rat renal cell carcinoma
A number of cancer genes have been identified by the study of hereditary human cancers and shown to be involved in sporadic… 
1995
1995
Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis(Tsc2)
We have recently identified on rat chromosome 10q a germline mutation in the tuberous sclerosis gene(Tsc2), the gene predisposing… 
Highly Cited
1994
Highly Cited
1994
The predisposing gene of the Eker rat inherited cancer syndrome is tightly linked to the tuberous sclerosis (TSC2) gene.
The Eker rat is a promising animal model of cancer predisposition syndromes. In this study, using 129 backcross animals, we have… 
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