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TRPP Cation Channels

Known as: TRPP Cation Channels [Chemical/Ingredient], Cation Channels, TRPP, Polycystins 
A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are associated with POLYCYSTIC KIDNEY DISEASES.
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (2)

polycystic kidney disease 1 proteinpolycystic kidney disease 2 protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Polycystin-1 cleavage and the regulation of transcriptional pathways
Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of end-stage renal disease, affecting… 
Review
2013
Review
2013
Multidrug Therapy for Polycystic Kidney Disease: A Review and Perspective
Autosomal dominant polycystic kidney disease (ADPKD) is a renal disorder characterized by the development of cysts in both… 
Highly Cited
2009
Highly Cited
2009
Characterization of primary cilia in human airway smooth muscle cells.
BACKGROUND Considerable evidence indicates a key role for primary cilia of mammalian cells in mechanochemical sensing… 
Review
2006
Review
2006
Molecular pathogenesis of autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest inherited human disorders yet remains relatively… 
Review
2005
Review
2005
Subcellular localization and trafficking of polycystins
Polycystin-2 is a member of the transient receptor potential (TRP) family of ion channels that is mutated in autosomal dominant… 
2005
2005
Primary cilia of inv/inv mouse renal epithelial cells sense physiological fluid flow: bending of primary cilia and Ca2+ influx.
Primary cilia are hypothesized to act as a mechanical sensor to detect renal tubular fluid flow. Anomalous structure of primary… 
Review
2004
Review
2004
Polycystins: what polycystic kidney disease tells us about sperm
Experimental evidence indicates that the membrane‐associated proteins polycystin‐1 and polycystin‐2 operate as a receptor‐calcium… 
2002
2002
Modulation of the human polycystin‐L channel by voltage and divalent cations
Review
2001
Review
2001
Autosomal dominant polycystic kidney disease: modification of disease progression
Highly Cited
1968
Highly Cited
1968
Radiolarian Skeletons: Solution at Depths
Radiolarian skeletons were placed at several depths on the taut mooring wire of a buoy in the central Pacific for 4 months… 
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