TRADD gene

Known as: TNFRSF1A-Associated via Death Domain Gene, TNFRSF1A-associated via death domain, TUMOR NECROSIS FACTOR RECEPTOR 1-ASSOCIATED DEATH DOMAIN PROTEIN 
This gene plays a role in signal transduction and regulation of apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Upon detection of viral RNA, the helicases RIG-I and/or MDA5 trigger, via their adaptor Cardif (also known as IPS-1, MAVS, or… (More)
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Highly Cited
2008
Highly Cited
2008
Tumor necrosis factor receptor 1 (TNFR1) and Toll-like receptors (TLRs) regulate immune and inflammatory responses. Here we show… (More)
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Highly Cited
2008
Highly Cited
2008
Tumor necrosis factor receptor 1-associated death domain protein (TRADD) is the core adaptor recruited to TNF receptor 1 (TNFR1… (More)
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Highly Cited
2002
Highly Cited
2002
Tumor necrosis factor receptor 1 (TNFR1) can trigger distinct signaling pathways leading to either the activation of NF-kappaB… (More)
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Highly Cited
2001
Highly Cited
2001
Keratin 8 and 18 (K8/18) are the major components of intermediate filament (IF) proteins of simple or single-layered epithelia… (More)
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Highly Cited
1999
Highly Cited
1999
The transforming Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) activates signalling on the NF-kappaB axis through… (More)
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Highly Cited
1997
Highly Cited
1997
IL-1 is a proinflammatory cytokine that signals through a receptor complex of two different transmembrane chains to generate… (More)
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Highly Cited
1997
Highly Cited
1997
Several members of the tumour-necrosis/nerve-growth factor (TNF/NGF) receptor family activate the transcription factor NF-KB… (More)
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Highly Cited
1996
Highly Cited
1996
Fas/APO-1 and p55 tumor necrosis factor (TNF) receptor (p55-R) activate cellular mechanisms that result in cell death. Upon… (More)
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Highly Cited
1995
Highly Cited
1995
Many diverse activities of tumor necrosis factor (TNF) are signaled through TNF receptor 1 (TNFRl). We have identified a novel 34… (More)
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