TP63 wt Allele

Known as: P73L, TP53CP, AIS 
Human TP63 wild-type allele is located in the vicinity of 3q28 and is approximately 266 kb in length. This allele, which encodes tumor protein 63, is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The epidermis, the outer layer of the skin composed of keratinocytes, is a stratified epithelium that functions as a barrier to… (More)
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Highly Cited
2006
Highly Cited
2006
Using tiled microarrays covering the entire human genome, we identify approximately 5800 target sites for p63, a p53 homolog… (More)
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Highly Cited
2002
Highly Cited
2002
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage… (More)
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Review
2002
Review
2002
Compared with many normal tissues, cancer cells are highly sensitized to apoptotic signals, and survive only because they have… (More)
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Highly Cited
2001
Highly Cited
2001
The proliferative compartment of stratified squamous epithelia consists of stem and transient amplifying (TA) keratinocytes. Some… (More)
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Highly Cited
2000
Highly Cited
2000
The p53 homologue p63 encodes for different isotypes able to either transactivate p53 reporter genes (TAp63) or act as p53… (More)
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Review
2000
Review
2000
The p53 gene is the most frequently mutated gene in human cancer. The identification of two homologues, p63 and p73, revealed… (More)
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Highly Cited
1999
Highly Cited
1999
The p53 tumour suppressor is a transcription factor that regulates the progression of the cell through its cycle and cell death… (More)
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Highly Cited
1999
Highly Cited
1999
The p63 gene, a homologue of the tumour-suppressor p53 (refs 1–5), is highly expressed in the basal or progenitor layers of many… (More)
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Highly Cited
1998
Highly Cited
1998
We describe the cloning of p63, a gene at chromosome 3q27-29 that bears strong homology to the tumor suppressor p53 and to the… (More)
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