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TP63 wt Allele

Known as: P73L, TP53CP, AIS 
Human TP63 wild-type allele is located in the vicinity of 3q28 and is approximately 266 kb in length. This allele, which encodes tumor protein 63, is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The distinguishing feature of adult stem cells is their extraordinary capacity to divide prior to the onset of senescence. While… Expand
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Review
2004
Review
2004
The tumor suppressor p53 is critically important in the cellular damage response and is the founding member of a family of… Expand
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Highly Cited
2002
Highly Cited
2002
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage… Expand
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Highly Cited
2001
Highly Cited
2001
The proliferative compartment of stratified squamous epithelia consists of stem and transient amplifying (TA) keratinocytes. Some… Expand
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Highly Cited
2000
Highly Cited
2000
The p53 homologue p63 encodes for different isotypes able to either transactivate p53 reporter genes (TAp63) or act as p53… Expand
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Review
2000
Review
2000
Inactivation of the tumour suppressor p53 is the most common defect in cancer cells. The discovery of its two close relatives… Expand
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Highly Cited
1999
Highly Cited
1999
The p63 gene, a homologue of the tumour-suppressor p53 (refs 1–5), is highly expressed in the basal or progenitor layers of many… Expand
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Highly Cited
1999
Highly Cited
1999
The p53 tumour suppressor is a transcription factor that regulates the progression of the cell through its cycle and cell death… Expand
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Highly Cited
1999
Highly Cited
1999
EEC syndrome is an autosomal dominant disorder characterized by ectrodactyly, ectodermal dysplasia, and facial clefts. We have… Expand
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Highly Cited
1998
Highly Cited
1998
We describe the cloning of p63, a gene at chromosome 3q27-29 that bears strong homology to the tumor suppressor p53 and to the… Expand
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