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TP53BP1 gene

Known as: 53BP1, TP53BP1, TUMOR PROTEIN p53-BINDING PROTEIN 1 
This gene may play a role in the modulation of the response to DNA damage.
National Institutes of Health

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Related topics

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Cell Cycle ControlDNA RepairTP53BP1 protein, humanTumor Suppressor p53-Binding Protein 1

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TP53BP1 wt Allele

Papers overview

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2017
2017
DNA repair genes PAXIP1 and TP53BP1 expression is associated with breast cancer prognosis
ABSTRACT Despite remarkable advances in diagnosis, prognosis and treatment, advanced or recurrent breast tumors have limited… 
2016
2016
Effects of carbon ion irradiation and X-ray irradiation on the ubiquitylated protein accumulation
C-ion radiotherapy is associated with improved local control and survival in several types of tumors. Although C-ion irradiation… 
2011
2011
Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.
How genetic variations in apoptosis pathway interact with environmental factors to contribute to esophageal adenocarcinoma (EA… 
2010
2010
Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu and the risk of lung cancer in a Japanese population.
The tumor suppressor protein p53 (TP53) plays a central role in directing cellular responses to DNA damage. Tumor protein 53… 
Highly Cited
2008
Highly Cited
2008
Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis
The importance of the DNA damage response (DDR) pathway in development, genomic stability, and tumor suppression is well… 
Review
2002
Review
2002
Interferon-inducible p202 in the susceptibility to systemic lupus.
Systemic lupus erythematosus (SLE) is the prototype systemic autoimmune disease, which has potential to involve multiple organ… 
2001
2001
p202, an interferon-inducible negative regulator of cell growth, is a target of the adenovirus E1A protein
Studies have revealed that human adenovirus-encoded E1A protein promotes cell proliferation through the targeted interaction with… 
Highly Cited
1998
Highly Cited
1998
Increase in p202 Expression during Skeletal Muscle Differentiation: Inhibition of MyoD Protein Expression and Activity by p202
ABSTRACT p202 is a primarily nuclear, interferon-inducible murine protein that is encoded by the Ifi 202 gene. Overexpression of… 
1998
1998
Increase in p 202 Expression during Skeletal Muscle Differentiation : Inhibition of MyoD Protein Expression and Activity by p 202 †
1996
1996
The interferon-inducible growth-inhibitory p202 protein: DNA binding properties and identification of a DNA binding domain.
p202 is an interferon-inducible protein whose expression in transfected cells inhibits proliferation. p202 binds to the… 
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