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TP53BP1 gene

Known as: 53BP1, TP53BP1, TUMOR PROTEIN p53-BINDING PROTEIN 1 
This gene may play a role in the modulation of the response to DNA damage.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
DNA double-strand breaks (DSBs) elicit a histone modification cascade that controls DNA repair. This pathway involves the… Expand
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Highly Cited
2013
Highly Cited
2013
53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand… Expand
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Highly Cited
2013
Highly Cited
2013
UNLABELLED Inhibition of PARP is a promising therapeutic strategy for homologous recombination-deficient tumors, such as BRCA1… Expand
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Highly Cited
2012
Highly Cited
2012
Recent genome-wide association studies (GWASs) have identified common genetic variants at 5p15.33, 6p21–6p22 and 15q25.1… Expand
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Highly Cited
2010
Highly Cited
2010
Class switch recombination (CSR) diversifies antibodies by joining highly repetitive DNA elements, which are separated by 60–200… Expand
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Highly Cited
2009
Highly Cited
2009
DNA double-strand breaks (DSBs) are highly cytotoxic lesions that are generated by ionizing radiation and various DNA-damaging… Expand
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Highly Cited
2009
Highly Cited
2009
Progressive telomere attrition or uncapping of the shelterin complex elicits a DNA damage response as a result of a cell’s… Expand
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Highly Cited
2004
Highly Cited
2004
The mammalian protein 53BP1 is activated in many cell types in response to genotoxic stress, including DNA double-strand breaks… Expand
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Highly Cited
1996
Highly Cited
1996
The antimicrobial, immunomodulatory, and cell growth-regulatory activities of the interferons are mediated by interferon… Expand
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Highly Cited
1995
Highly Cited
1995
Many of the antimicrobial, immunomodulatory, and cell growth regulatory activities of the interferons are mediated by interferon… Expand
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