TP53BP1 gene

Known as: 53BP1, TP53BP1, TUMOR PROTEIN p53-BINDING PROTEIN 1 
This gene may play a role in the modulation of the response to DNA damage.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
DNA double-strand breaks (DSBs) are highly cytotoxic lesions that are generated by ionizing radiation and various DNA-damaging… (More)
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Highly Cited
2008
Highly Cited
2008
The importance of the DNA damage response (DDR) pathway in development, genomic stability, and tumor suppression is well… (More)
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Highly Cited
2007
Highly Cited
2007
Cellular DNA double-strand break-repair pathways have evolved to protect the integrity of the genome from a continual barrage of… (More)
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Highly Cited
2006
Highly Cited
2006
Here we document the role of MDC1 (mediator of DNA damage checkpoint 1) in the detection and repair of human and mouse telomeres… (More)
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Highly Cited
2006
Highly Cited
2006
53BP1 (p53 binding protein) is a BRCT domain-containing protein that is rapidly recruited to DNA double strand breaks (DSBs). To… (More)
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Highly Cited
2005
Highly Cited
2005
High-resolution genome-wide mapping of exact boundaries of chromosomal alterations should facilitate the localization and… (More)
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Highly Cited
2004
Highly Cited
2004
The mammalian protein 53BP1 is activated in many cell types in response to genotoxic stress, including DNA double-strand breaks… (More)
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1998
1998
p202 is a primarily nuclear, interferon-inducible murine protein that is encoded by the Ifi 202 gene. Overexpression of p202 in… (More)
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Highly Cited
1996
Highly Cited
1996
The antimicrobial, immunomodulatory, and cell growth-regulatory activities of the interferons are mediated by interferon… (More)
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1995
1995
Many of the antimicrobial, immunomodulatory, and cell growth regulatory activities of the interferons are mediated by interferon… (More)
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