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TP53BP1 protein, human

Known as: p53-Binding Protein 1, 53BP1, p202 protein, human 
Tumor suppressor p53-binding protein 1 (1972 aa, ~214 kDa) is encoded by the human TP53BP1 gene. This protein may play a role in nonhomologous end… 
National Institutes of Health

Papers overview

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2013
2013
Chemoresistance of breast cancer is a worldwide problem for breast cancer and the resistance to chemotherapeutic agents… 
2012
2012
Cell cycle regulation and DNA repair following damage are essential for maintaining genome integrity. DNA damage activates… 
2011
2011
Abstract We have previously shown that the Ser15-phosphorylated p53 phosphoform, p53Ser15, can localize at sites of ionizing… 
2011
2011
Persistent infections by high-risk types of human papillomavirus (HPV) have been established as the etiological agent of cervical… 
Highly Cited
2008
Highly Cited
2008
The DNA damage surveillance network orchestrates cellular responses to DNA damage through the recruitment of DNA damage-signaling… 
2007
2007
BACKGROUND & OBJECTIVE 53BP1 is one of p53-binding proteins, which can enhance the transcriptional activation of p53 and plays a… 
Highly Cited
2006
Highly Cited
2006
Deregulation of the Rb/E2F pathway in human fibroblasts results in an E2F1-mediated apoptosis dependent on Atm, Nbs1, Chk2 and… 
2006
2006
Oogenesis is a critical event in the formation of gametes, which transfer genomic information to the next generation. During this… 
2005
2005
Purpose: p53-binding protein 1 (53BP1), a participant in the DNA damage response pathway, has also been implicated in the…