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TP53BP1 protein, human
Known as:
p53-Binding Protein 1
, 53BP1
, p202 protein, human
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Tumor suppressor p53-binding protein 1 (1972 aa, ~214 kDa) is encoded by the human TP53BP1 gene. This protein may play a role in nonhomologous end…
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National Institutes of Health
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Related topics
Related topics
8 relations
Cell Cycle Control
DNA Repair
Genes, Regulator
Genes, cdc
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Broader (2)
TP53BP1 wt Allele
Tumor Suppressor p53-Binding Protein 1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
53BP1 Sensitizes Breast Cancer Cells to 5-Fluorouracil
Xiaoyan Li
,
Xiaoli Kong
,
Xiangnan Kong
,
Yang Wang
,
Shi Yan
,
Qifeng Yang
PLoS ONE
2013
Corpus ID: 12442260
Chemoresistance of breast cancer is a worldwide problem for breast cancer and the resistance to chemotherapeutic agents…
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2012
2012
Alteration/deficiency in activation-3 (Ada3) plays a critical role in maintaining genomic stability
S. Mirza
,
Bryan J. Katafiasz
,
+8 authors
V. Band
Cell Cycle
2012
Corpus ID: 12408937
Cell cycle regulation and DNA repair following damage are essential for maintaining genome integrity. DNA damage activates…
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2011
2011
Protein-Protein Interactions Occur Between p53 Phosphoforms and ATM and 53BP1 at Sites of Exogenous DNA Damage
Shahnaz T Al Rashid
,
S. Harding
,
C. Law
,
C. Coackley
,
R. Bristow
Radiation Research
2011
Corpus ID: 33901510
Abstract We have previously shown that the Ser15-phosphorylated p53 phosphoform, p53Ser15, can localize at sites of ionizing…
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2011
2011
Genetic polymorphisms and cervical cancer development: ATM G5557A and p53bp1 C1236G
S. Oliveira
,
J. Ribeiro
,
H. Sousa
,
Décio dos Santos Pinto
,
I. Baldaque
,
Rui Medeiros
Oncology Report
2011
Corpus ID: 675742
Persistent infections by high-risk types of human papillomavirus (HPV) have been established as the etiological agent of cervical…
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Review
2010
Review
2010
The interplay between BRCA1 and 53BP1 influences death, aging, senescence and cancer.
N. Lowndes
DNA Repair
2010
Corpus ID: 1084051
Highly Cited
2008
Highly Cited
2008
RNF8-dependent and RNF8-independent Regulation of 53BP1 in Response to DNA Damage*
Ryo Sakasai
,
R. Tibbetts
Journal of Biological Chemistry
2008
Corpus ID: 21284356
The DNA damage surveillance network orchestrates cellular responses to DNA damage through the recruitment of DNA damage-signaling…
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2007
2007
[Correlation of 53BP1 and p53 polymorphisms to susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma].
Yan-yan Cao
,
H. Ge
,
+4 authors
Jian-hui Zhang
Ai zheng = Aizheng = Chinese journal of cancer
2007
Corpus ID: 21467304
BACKGROUND & OBJECTIVE 53BP1 is one of p53-binding proteins, which can enhance the transcriptional activation of p53 and plays a…
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Highly Cited
2006
Highly Cited
2006
E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts
FM Frame
,
Harry A. Rogoff
,
MT Pickering
,
W. Cress
,
TF Kowalik
Oncogene
2006
Corpus ID: 37038657
Deregulation of the Rb/E2F pathway in human fibroblasts results in an E2F1-mediated apoptosis dependent on Atm, Nbs1, Chk2 and…
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2006
2006
Stage specific expression of histone deacetylase 4 (HDAC4) during oogenesis and early preimplantation development in mice.
S. Kageyama
,
Honglin Liu
,
M. Nagata
,
F. Aoki
Journal of reproduction and development
2006
Corpus ID: 21619135
Oogenesis is a critical event in the formation of gametes, which transfer genomic information to the next generation. During this…
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2005
2005
Jun activation domain-binding protein 1 is required for mitotic checkpoint activation via its involvement in hyperphosphorylation of 53BP1
H. Kwak
,
Sung Hak Kim
,
H. Yoo
,
S. Park
,
Chang-Hun Lee
Journal of Cancer Research and Clinical Oncology
2005
Corpus ID: 9079521
Purpose: p53-binding protein 1 (53BP1), a participant in the DNA damage response pathway, has also been implicated in the…
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