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TP53 gene

Known as: TUMOR PROTEIN p53, Tumor Protein P53 (Li-Fraumeni Syndrome) Gene, Gene, TP53 
Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53.
National Institutes of Health

Related topics

Related topics

50 relations
Adenocarcinoma of the large intestineBowen's DiseaseBronchioloalveolar AdenocarcinomaCarcinoma in situ of penis

Papers overview

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Review
1999
Review
1999
A new approach to risk estimation of food-borne carcinogens--heterocyclic amines--based on molecular information.
  • M. Nagao
  • Mutation research
  • 1999
  • Corpus ID: 11577636
Highly Cited
1998
Highly Cited
1998
Superoxide formation and DNA damage induced by a fragrant furanone in the presence of copper(II).
Highly Cited
1998
Highly Cited
1998
Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo.
The mutational specificity of UV-light is characterized by an abundance of C to T transition mutations at dipyrimidines… 
Highly Cited
1997
Highly Cited
1997
Genetic alterations of p16INK4a and p53 genes in sporadic dysplastic nevus.
It is still unclear whether the sporadic form of dysplastic nevi (SDN) represents a premalignant lesion of malignant melanoma and… 
Highly Cited
1994
Highly Cited
1994
Mutations of the p53 tumor suppressor gene occur infrequently in Wilms' tumor.
Mutations of the p53 tumor suppressor gene occur frequently in a variety of adult-onset tumors, including colon, breast, lung… 
Review
1994
Review
1994
Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?
Highly Cited
1993
Highly Cited
1993
Simple sequence repeat polymorphism within the p53 gene.
This report describes a new polymorphism, in intron 3 of the p53 gene, which consists of a single repeat of 16 nucleotides… 
Highly Cited
1993
Highly Cited
1993
Novel DNA binding of p53 mutants and their role in transcriptional activation.
The protein product of the normal p53 gene binds to the DNA p53CON element (GGACATGCCCGGGCATGTCC, Funk et al., 1992), thereby… 
Highly Cited
1993
Highly Cited
1993
Detection of immunoglobulin gene rearrangement of B cell non-Hodgkin's lymphomas and leukemias in fresh, unfixed and formalin-fixed, paraffin-embedded tissue by polymerase chain reaction.
BACKGROUND The majority of B cell nonHodgkin's lymphomas (NHLs) are composed of a genotypically identical cell population… 
Highly Cited
1992
Highly Cited
1992
Mutations of the p53 gene in human myeloma cell lines.
Mutations affecting the p53 gene have been found associated with many human malignancies, but little is as yet known about… 
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