TORC2 complex location

Known as: TOR complex location 2, TORC2, TORC 2 complex location 
A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Rapamycin, an inhibitor of mechanistic target of rapamycin complex 1 (mTORC1), extends the life spans of yeast, flies, and mice… (More)
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Highly Cited
2010
Highly Cited
2010
The mechanisms that couple translation and protein processing are poorly understood in higher eukaryotes. Although mammalian… (More)
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Highly Cited
2009
Highly Cited
2009
The mammalian target of rapamycin (mTOR) regulates cell growth and survival by integrating nutrient and hormonal signals. These… (More)
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Highly Cited
2009
Highly Cited
2009
The mammalian target of rapamycin (mTOR) functions within two distinct complexes (mTORC1 and mTORC2) to control cell growth… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Mammalian target of rapamycin complex 1 (mTORC1) is a protein kinase that relays nutrient availability signals to… (More)
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Highly Cited
2009
Highly Cited
2009
mTOR, the mammalian target of rapamycin, is a critical node for control of cell growth and survival and has widely been… (More)
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Highly Cited
2008
Highly Cited
2008
The mammalian target of rapamycin (mTOR) is a protein kinase that forms two functionally distinct complexes important for… (More)
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Highly Cited
2008
Highly Cited
2008
The target of rapamycin (TOR), as part of the rapamycin-sensitive TOR complex 1 (TORC1), regulates various aspects of protein… (More)
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Highly Cited
2007
Highly Cited
2007
A central regulator of cell growth that has been implicated in responses to stress such as hypoxia is mTOR (mammalian Target Of… (More)
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Highly Cited
2007
Highly Cited
2007
mTORC2 is a multimeric kinase composed of the mammalian target of rapamycin kinase (mTOR), mLST8, mSin1, and rictor. The complex… (More)
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