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CRTC2 gene

Known as: CREB-REGULATED TRANSCRIPTION COACTIVATOR 2, TORC2, TRANSDUCER OF REGULATED cAMP RESPONSE ELEMENT-BINDING PROTEIN 2 
This gene is involved in transcriptional activation.
National Institutes of Health

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CRTC2 wt Allele
Homo sapiensSignal TransductionTORC2 complex locationTranscriptional Activation

Papers overview

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2018
2018
Suppression of gluconeogenic gene transcription by SIK1-induced ubiquitination and degradation of CRTC1.
2016
2016
Novel role for the CRTC2 in lipid homeostasis
The mTOR pathways involved in the regulation of SREBP‐1. 
2015
2015
Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2…
2015
2015
CRTC2 and Nedd4 ligase involvement in FSH and TGFβ1 upregulation of connexin43 gap junction.
The major mission of the ovarian follicle is the timely production of the mature fertilizable oocyte, and this is achieved by… 
2015
2015
Association of CRTC2 gene polymorphisms with growth and meat quality traits of Qinchuan cattle.
Growth and meat quality traits play important roles in the evaluation of cattle productivity and are influenced by genetic and… 
2014
2014
CRTC2 and PROM1 expression in non-small cell lung cancer: analysis by Western blot and immunohistochemistry
Accumulating evidence supports that genetic factors are another risk factors for lung cancer. Previously, we used whole exome… 
2014
2014
CRTC2 activation in the suprachiasmatic nucleus, but not paraventricular nucleus, varies in a diurnal fashion and increases with nighttime light exposure.
Entrainment of the intrinsic suprachiasmatic nucleus (SCN) molecular clock to the light-dark cycle depends on photic-driven… 
2012
2012
Diabetes: Insulin signal meets SIRT1 at AKT
Insulin resistance is a characteristic feature of type 2 diabetes mellitus. The activation of SIRT1, a deacetylase, is reported… 
2011
2011
Ageing: Staying alive without CRTC-1
Activation of AMP-activated protein kinase (AMPK) or inactivation of the phosphatase calcineurin slows ageing in Caenorhabditis… 
2009
2009
Metformin Inhibits Aromatase Expression in Primary Human Breast Adipose Stromal Cells.
There is good epidemiological evidence that obesity is linked to an increased risk of cancers such as colon and breast. Given the… 
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