TOR complex 1

Known as: TORC1 complex location, dTORC1, rapamycin and nutrient-sensitive TOR complex 
A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The TOR kinase, which is present in the functionally distinct complexes TORC1 and TORC2, is essential for growth but associated… (More)
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2012
2012
The TOR complex 1 (TORC1) in yeast is regulated by various stress conditions. However, the underlying mechanism is poorly… (More)
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Highly Cited
2011
Highly Cited
2011
Hyperglycemia induces a wide array of signaling pathways in the kidney that lead to hypertrophy and matrix expansion, eventually… (More)
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Review
2011
Review
2011
The target of rapamycin (TOR) is a central cell growth regulator conserved from yeast to mammals. Uncontrolled TOR activation is… (More)
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Highly Cited
2011
Highly Cited
2011
Sirt1, a NAD-dependent protein deacetylase, has emerged as a key regulator of mammalian transcription in response to cellular… (More)
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Review
2009
Review
2009
Research on TOR has grown exponentially during the last decade, generating a complex model of the TOR signaling network… (More)
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Highly Cited
2008
Highly Cited
2008
Cell growth (accumulation of mass) needs to be coordinated with metabolic processes that are required for the synthesis of… (More)
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Highly Cited
2007
Highly Cited
2007
Fission yeast has two TOR (target of rapamycin) kinases, namely Tor1 and Tor2. Tor1 is required for survival under stressed… (More)
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Highly Cited
2007
Highly Cited
2007
The Target of Rapamycin (TOR) protein is a Ser/Thr kinase that functions in two distinct multiprotein complexes: TORC1 and TORC2… (More)
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Highly Cited
2004
Highly Cited
2004
The target of rapamycin (TOR) is a highly conserved protein kinase and a central controller of cell growth. In budding yeast, TOR… (More)
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