FAQ

CREB-Regulated Transcription Coactivator 1

Known as: Mucoepidermoid Carcinoma Translocated Protein 1, CRTC1, Transducer of Regulated cAMP Response Element-Binding Protein 1 
CREB-regulated transcription coactivator 1 (634 aa, ~67 kDa) is encoded by the human CRTC1 gene. This protein plays a role in the activation of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
02420062017

Related topics

Related topics

12 relations
AdenolymphomaCRTC1 geneClear cell hidradenomaGenes, Regulator
(More)

Broader (1)

CRTC1 wt Allele

Related mentions per year

Related mentions per year

1942-2018
19401960198020002020
CREB-Regulated Transcription Coactivator 1
Signal Transduction
Genes, Regulator
protein protein interaction
Transcriptional Regulation
Adenolymphoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Region-Specific Activation of CRTC1-CREB Signaling Mediates Long-Term Fear Memory
CREB is a pivotal mediator of activity-regulated gene transcription that underlies memory formation and allocation. The… (More)
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2013
2013
The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock
Retinal photoreceptors entrain the circadian system to the solar day. This photic resetting involves cAMP response element… (More)
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2013
2013
Clock and light regulation of the CREB coactivator CRTC1 in the suprachiasmatic circadian clock.
The CREB/CRE transcriptional pathway has been implicated in circadian clock timing and light-evoked clock resetting. To date… (More)
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Highly Cited
2012
Highly Cited
2012
Activity-Dependent Transport of the Transcriptional Coactivator CRTC1 from Synapse to Nucleus
Long-lasting changes in synaptic efficacy, such as those underlying long-term memory, require transcription. Activity-dependent… (More)
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2010
2010
beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1.
Activity-dependent gene expression mediating changes of synaptic efficacy is important for memory storage, but the mechanisms… (More)
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2009
2009
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Regulation of gene expression in response to mitogenic stimuli is a critical aspect underlying many forms of human cancers. The… (More)
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2009
2009
Prognostic significance of p27Kip1, Ki-67, and CRTC1-MAML2 fusion transcript in mucoepidermoid carcinoma: a molecular and clinicopathologic study of 101 cases.
PURPOSE Mucoepidermoid carcinoma (MEC) is the most frequently detected primary malignancy of the salivary gland and is… (More)
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2009
2009
Mucoepidermoid carcinoma of the cervix: another tumor with the t(11;19)-associated CRTC1-MAML2 gene fusion.
Mucoepidermoid carcinoma (MEC) of the uterine cervix is a controversial entity. By strict morphologic criteria, the tumor has… (More)
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2007
2007
Frequent fusion of the CRTC1 and MAML2 genes in clear cell variants of cutaneous hidradenomas.
Fusion of the CREB regulated transcription coactivator CRTC1 (a.k.a. MECT1, TORC1, or WAMTP1) to the Notch coactivator MAML2 is a… (More)
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Highly Cited
2006
Highly Cited
2006
Molecular classification of mucoepidermoid carcinomas-prognostic significance of the MECT1-MAML2 fusion oncogene.
Mucoepidermoid carcinomas (MECs) of the salivary and bronchial glands are characterized by a recurrent t(11;19)(q21;p13… (More)
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