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CREB-Regulated Transcription Coactivator 1

Known as: Mucoepidermoid Carcinoma Translocated Protein 1, CRTC1, Transducer of Regulated cAMP Response Element-Binding Protein 1 
CREB-regulated transcription coactivator 1 (634 aa, ~67 kDa) is encoded by the human CRTC1 gene. This protein plays a role in the activation of… Expand
National Institutes of Health

Related topics

Related topics

12 relations
AdenolymphomaCRTC1 geneClear cell hidradenomaGenes, Regulator
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Broader (1)

CRTC1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement
Recent evidence demonstrates that epigenetic regulation of gene transcription is critically involved in learning and memory. Here… Expand
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2017
2017
CRTC1 mediates preferential transcription at neuronal activity-regulated CRE/TATA promoters
Gene expression mediated by the transcription factor cAMP-responsive element-binding protein (CREB) is essential for a wide range… Expand
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2016
2016
CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice
Background cAMP response element binding protein (CREB)-dependent gene expression plays an important role in central… Expand
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2016
2016
Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth
First identified as a dedicated CREB (cAMP response element-binding protein) co-activator, CRTC1 (CREB-regulated transcription co… Expand
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2014
2014
Requirement of CRTC1 coactivator for hepatitis B virus transcription
Transcription of hepatitis B virus (HBV) from the covalently closed circular DNA (cccDNA) template is essential for its… Expand
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Review
2014
Review
2014
Title Requirement of CRTC 1 coactivator for hepatitis B virustranscription
Transcription of hepatitis B virus (HBV) from the covalently closed circular DNA (cccDNA) template is essential for its… Expand
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Review
2013
Review
2013
Mitochondrial diseases of the brain.
Neurodegenerative disorders are debilitating diseases of the brain, characterized by behavioral, motor and cognitive impairments… Expand
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Highly Cited
2012
Highly Cited
2012
Activity-Dependent Transport of the Transcriptional Coactivator CRTC1 from Synapse to Nucleus
Long-lasting changes in synaptic efficacy, such as those underlying long-term memory, require transcription. Activity-dependent… Expand
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2012
2012
CREB-Regulated Transcription Coactivator 1-Dependent Transcription in Alzheimer’s Disease Mice
  • C. Saura
  • Neurodegenerative Diseases
  • 2012
    • Corpus ID: 30859860
Background/Aims: Long-term memory requires fine-tuning regulation of gene expression in specific neural circuits of the brain… Expand
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Highly Cited
2010
Highly Cited
2010
Regulation of Dendritic Development by BDNF Requires Activation of CRTC1 by Glutamate*
Dendritic growth is essential for the establishment of a functional nervous system. Among extrinsic signals that control… Expand
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