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DNA post‐replication repair (PRR) functions to bypass replication‐blocking lesions and prevent damage‐induced cell death. PRR… Expand Hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. The transcription factor hypoxia… Expand Human solid tumors contain hypoxic regions that have considerably lower oxygen tension than the normal tissues. Hypoxia offers… Expand Solid tumors containing more hypoxic regions show a more malignant phenotype by increasing the expression of genes encoding… Expand Tumor hypoxia in a solid tumor mass has long been recognized as a cause of resistance to current cancer therapies, and has also… Expand In Schizosaccharomyces pombe, topoisomerase III is encoded by a single gene, top3+, which is essential for cell viability and… Expand Three different schemes of topography-based runoff production [versatile integrator of surface atmospheric processes (VISA)-TOP1… Expand The Saccharomyces cerevisiae TOP3 gene encodes the type IA topoisomerase (Top3p) that is highly conserved in evolution. Deletion… Expand A mutant allele of SGS1 of Saccharomyces cerevisiae was identified as a suppressor of the slow-growth phenotype of top3 mutants… Expand ABSTRACT Deletion of the Saccharomyces cerevisiae TOP3gene, encoding Top3p, leads to a slow-growth phenotype characterized by an… Expand