TOP3A wt Allele

Known as: TOP3, Topoisomerase (DNA) III Alpha wt Allele 
Human TOP3A wild-type allele is located within 17p12-p11.2 and is approximately 41 kb in length. This allele, which encodes DNA topoisomerase 3-alpha… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
DNA post-replication repair (PRR) functions to bypass replication-blocking lesions and prevent damage-induced cell death. PRR… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. The transcription factor hypoxia… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Human solid tumors contain hypoxic regions that have considerably lower oxygen tension than the normal tissues. Hypoxia offers… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
Hypoxia is a common feature of solid tumors and is associated with their malignant phenotype. The transcription factor hypoxia… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2006
2006
Under normoxic conditions the alpha-subunit of hypoxia-inducible factor (HIF-1alpha) protein is targeted for degradation by the… (More)
Is this relevant?
2005
2005
Solid tumors containing more hypoxic regions show a more malignant phenotype by increasing the expression of genes encoding… (More)
Is this relevant?
2004
2004
In Schizosaccharomyces pombe, topoisomerase III is encoded by a single gene, top3(+), which is essential for cell viability and… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2003
2003
Three different schemes of topography-based runoff production [versatile integrator of surface atmospheric processes (VISA)-TOP1… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
2002
2002
The Saccharomyces cerevisiae TOP3 gene encodes the type IA topoisomerase (Top3p) that is highly conserved in evolution. Deletion… (More)
Is this relevant?
2001
2001
Deletion of the Saccharomyces cerevisiae TOP3 gene, encoding Top3p, leads to a slow-growth phenotype characterized by an… (More)
Is this relevant?