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TOLLIP protein, human

Known as: Toll-interacting protein, human, toll interacting protein, human, Toll-Interacting Protein 
Encoded by human TOLLIP Gene, 274-aa 30-kDa oligomeric Toll-Interacting Protein, containing a CUE domain, is involved in IL-1 and Toll-like receptor… 
National Institutes of Health

Related topics

Related topics

9 relations
Adaptor Proteins, Signal TransducingAdaptor Signaling Protein GeneBeta-Catenin Accumulation PathwayIL1R Signaling Pathway

Papers overview

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Highly Cited
2012
Highly Cited
2012
Expression of Microbiota, Toll-like Receptors, and Their Regulators in the Small Intestinal Mucosa in Celiac Disease
Objectives: Less than one-tenth of the carriers of the risk genes HLA-DQ2 or HLA-DQ8 develop celiac disease, suggesting that… 
2011
2011
Variants in the Toll-interacting protein gene are associated with susceptibility to sepsis in the Chinese Han population
IntroductionDeregulated or excessive host immune responses contribute to the pathogenesis of sepsis. Toll-like receptor (TLR… 
Highly Cited
2007
Highly Cited
2007
Caveolin-1 Triggers T-cell Activation via CD26 in Association with CARMA1*
CD26 is a widely distributed 110-kDa cell surface glycoprotein with an important role in T-cell costimulation. We demonstrated… 
Highly Cited
2006
Highly Cited
2006
Intracellular Trafficking of Interleukin-1 Receptor I Requires Tollip
Review
2005
Review
2005
Intestinal epithelial TOLLerance versus inTOLLerance of commensals.
Highly Cited
2004
Highly Cited
2004
Sequential Autophosphorylation Steps in the Interleukin-1 Receptor-associated Kinase-1 Regulate its Availability as an Adapter in Interleukin-1 Signaling*
The interleukin-1 receptor-associated kinase 1 (IRAK-1) is an important adapter in the signaling complex of the Toll/interleukin… 
Highly Cited
2004
Highly Cited
2004
Tollip and Tom1 Form a Complex and Recruit Ubiquitin-conjugated Proteins onto Early Endosomes*
Tom1 (target of Myb1) is a protein of unknown function. Tom1 and its relative Tom1L1 have an N-terminal VHS (Vps27p/Hrs/Stam… 
Highly Cited
2003
Highly Cited
2003
Tom1, a VHS Domain-containing Protein, Interacts with Tollip, Ubiquitin, and Clathrin*
The gene for Tom1 was initially identified as a specific target of the oncogene v-myb. The Tom1 protein belongs to the VHS domain… 
Review
2002
Review
2002
Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily.
Toll-like receptors (TLRs) are an important point of first contact between host and microbe, and once activated generate signals… 
Review
2000
Review
2000
The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence.
The pro-inflammatory cytokine interleukin-1 (IL-1) signals via the Type-I IL-1 receptor (IL-1RI), inducing an increase in the… 
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